Results 51 to 60 of about 6,984 (265)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Generalized symmetries of impulsive gravitational waves [PDF]

open access: yesClassical and Quantum Gravity, 1997
We generalize previous \cite{AiBa2} work on the classification of ($C^\infty$) symmetries of plane-fronted waves with an impulsive profile. Due to the specific form of the profile it is possible to extend the group of normal-form-preserving diffeomorphisms to include non-smooth transformations.
Aichelburg, Peter C., Balasin, Herbert
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

IR-UWB antenna with built-in impulse-like waveform generator for impulse radar applications

open access: yesAIP Advances
This paper presents a novel impulse-radio ultra-wideband (IR-UWB) pulsed radar antenna integrated with an impulse generator circuit, designed and investigated for IR-UWB radar imaging applications.
D. Lee
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Impulse noise generated by starter pistols [PDF]

open access: yesInternational Journal of Audiology, 2013
This study describes signals generated by .22 and .32 caliber starter pistols in the context of noise-induced hearing loss risk for sports officials and athletes.Acoustic comparison of impulses generated from typical .22 and .32 caliber starter pistols firing blanks were made to impulses generated from comparable firearms firing both blanks and live ...
Deanna K, Meinke   +6 more
openaire   +2 more sources

新型脉动发生机构研究及运动仿真

open access: yesJixie chuandong, 2006
Structural characteristics and kinematics feature of a new impulse generator are analyzed. The relations of theoretical outline of cam, swing angle of rocker and dimension of link are established.
杨刚   +4 more
doaj  

Grid connection method of gravity energy storage generator motor based on voltage index sensitivity analysis

open access: yesEnergy Informatics
The basic requirements for the grid connection of the generator motor of the gravity energy storage system are: the phase sequence, frequency, amplitude, and phase of the voltage at the generator end and the grid end must be consistent.
Qingshan Wang   +3 more
doaj   +1 more source

Nd-Fe-B permanent magnet generator and voltage stabilizing control technology for vehicles

open access: yesAdvances in Mechanical Engineering, 2016
In this study, the tangential magnetic field Nd-Fe-B permanent magnet generator is designed and analyzed. In the generator, the adjacent permanent steel is sequentially arranged on the radial groove by the way of same polarity-oriented manner.
Xueyi Zhang   +6 more
doaj   +1 more source

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