Results 51 to 60 of about 5,343,533 (295)

Measurement of High-Power Microwave Impulse Response Characteristics of Reflector Materials

open access: yesInternational Journal of Antennas and Propagation
High-power microwave (HPM) antenna, one of the key subsystems in the HPM system, is used for HPM radiation. Its performance is partly determined by the impulse responses of reflector materials under HPM.
Xianggang Hu   +10 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Adaptive Parameter Identification Based on Morlet Wavelet and Application in Gearbox Fault Feature Detection

open access: yesEURASIP Journal on Advances in Signal Processing, 2010
Localized defects in rotating mechanical parts tend to result in impulse response in vibration signal, which contain important information about system dynamics being analyzed.
Wang Shibin   +3 more
doaj  

An improved rotating HF signal injection method based on FIR filters for state estimation of BPMSM sensorless control

open access: yesAdvances in Mechanical Engineering, 2017
An improved rotating high-frequency signal injection method based on a finite impulse-response filter for state estimation of bearingless permanent magnet synchronous motor sensorless control is developed in this article.
Wei Ji, Guoding Shi, Bo Xu, Jian Xu
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Applications of Multifractals in the Analysis of Room Impulse Response - Initial Research [PDF]

open access: yesTelfor Journal, 2011
The analysis of impulse response has a central place in room acoustics. The research presented in this paper was aimed at examining possibilities for applying multifractal theory in room acoustics focusing on the analysis of room impulse response ...
M. Pavlović, D. M. Ristić
doaj  

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Surrogate impulse ground motion for practical simulation of critical nonlinear structural responses

open access: yesFrontiers in Built Environment
Impulse-based representations of earthquake ground motions provide an efficient framework for evaluating critical nonlinear structural responses. However, the direct use of ideal impulse ground motions expressed by Dirac’s delta function may excite all ...
Hiroki Akehashi   +5 more
doaj   +1 more source

Load Localization and Reconstruction Using a Variable Separation Method

open access: yesShock and Vibration, 2019
Load identification is very important in engineering practice. In this paper, a novel method for load reconstruction and localization is proposed. In the traditional load localization method, location information is coupled to the impulse response matrix.
Jing Zhang, Fang Zhang, Jinhui Jiang
doaj   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

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