Results 51 to 60 of about 116,303 (310)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Computing Impulse Response of Room Acoustics Using the Ray-Tracing Method in Time Domain
Archives of Acoustics, 2013 This paper proposes a new approach for calculating the impulse response of room acoustics. Impulse response provides unique characterization of any discrete linear-time invariant (LTI) systems.
Adil ALPKOCAK, Malik Kemal SIS
doaj
浙江大学学报. 农业与生命科学版, 2005 Using nondestructive acoustic impulse-response technique to evaluate the quality of oranges, it was found that there were lots of factors affecting dominant impulse-response frequency, such as mass, density, pH value, firmness and sugar content ...
HUANG Hui-ming +4 more
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Closed form metrics to accurately model the response in general arbitrarily-coupled RC trees. [PDF]
, 2003 Closed form expressions are presented for the first and second moment of the impulse response for arbitrarily-coupled RC trees with multiple drivers, and used to generate accurate second order estimations of the transfer function from any driver to the ...
Elassaad, Shauki +2 more
core +1 more source
Frontiers in Built EnvironmentA triple impulse is used as a mathematical model of forward-directivity inputs, which are fault-normal components of near-fault earthquake ground motions. In this paper, two types of the triple impulse input are employed.
Kotaro Kojima, Izuru Takewaki
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Impulse Response Analysis at the Zero Lower Bound [PDF]
, 2023 We study whether the response of the economy to structural shocks changes at the zero lower bound. Monte Carlo evidence suggests that VARs have a limited ability to detect changes in impulse response functions at the ZLB compared to the standard ...
Benati, Luca, Lubik, Thomas A.
core
Impulse Response Confidence Intervals for Persistent Data: What Have We Learned? [PDF]
This paper is a comprehensive comparison of existing methods for constructing confidence bands for univariate impulse response functions in the presence of high persistence.
Elena Pesavento, Barbara Rossi
core +2 more sources