Results 51 to 60 of about 123,096 (288)

Oscillation of high order linear functional differential equation with impulses

Electronic Journal of Differential Equations, 2005
We study the solutions to high-order linear functional differential equations with impulses. We improve previous results in the oscillation theory for ordinary differential equations and obtain new criteria on the oscillation of solutions.
Haihua Liang, Weizhen Feng
doaj  

The Strict Stability of Impulsive Differential Equations with a Caputo Fractional Derivative with Respect to Other Functions

Fractal and Fractional
The aim of this paper is to study a nonlinear system of impulsive fractional differential equations and Caputo fractional derivatives with respect to another function (CFF).
Ravi P. Agarwal, Snezhana Hristova, Donal O’Regan   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Positive periodic solutions for discrete time-delay hematopoiesis model with impulses

Open Mathematics, 2023
The present article is devoted to the positive periodic solution for impulsive discrete hematopoiesis model. This model is described by a first-order nonlinear difference equation with multiple delays and impulses.
Yan Yan
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Stability of Differential Equations with Random Impulses and Caputo-Type Fractional Derivatives

Axioms
In this paper, we study nonlinear differential equations with Caputo fractional derivatives with respect to other functions and impulses. The main characteristic of the impulses is that the time between two consecutive impulsive moments is defined by ...
Snezhana Hristova, Billur Kaymakçalan, Radoslava Terzieva   +2 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

On an Impulsive Conformable M1 Oncolytic Virotherapy Neural Network Model: Stability of Sets Analysis

Mathematics
In this paper, the impulsive conformable calculus approach is applied to the introduction of an M1 oncolytic virotherapy neural network model. The proposed model extends some existing mathematical models that describe the dynamics of the concentrations ...
Gani Stamov, Ivanka Stamova, Cvetelina Spirova   +2 more
doaj   +1 more source