Results 71 to 80 of about 91,295 (314)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
, 2000 This music score was submitted for the Kaleidoscope 2020 Call for Scores, an open access collaboration with the UCLA Music Library.
openaire +2 more sources
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Existence of solutions for impulsive neutral functional differential equations with multiple delays
Electronic Journal of Differential Equations, 2008 In this paper an existence result for initial value problems for first order impulsive neutral functional differential equations with multiple delay is proved under weak conditions.
Mustapha Lakrib
doaj
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Oscillation of high order linear functional differential equation with impulses
Electronic Journal of Differential Equations, 2005 We study the solutions to high-order linear functional differential equations with impulses. We improve previous results in the oscillation theory for ordinary differential equations and obtain new criteria on the oscillation of solutions.
Haihua Liang, Weizhen Feng
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Fractal and FractionalThe aim of this paper is to study a nonlinear system of impulsive fractional differential equations and Caputo fractional derivatives with respect to another function (CFF).
Ravi P. Agarwal +2 more
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Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Positive periodic solutions for discrete time-delay hematopoiesis model with impulses
Open Mathematics, 2023 The present article is devoted to the positive periodic solution for impulsive discrete hematopoiesis model. This model is described by a first-order nonlinear difference equation with multiple delays and impulses.
Yan Yan
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source