Results 51 to 60 of about 63,741 (268)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

The Archival Impulse and the Editorial Impulse [PDF]

open access: yesVariants, 2019
There is no firm, outside vantage-point from which to survey and thus to define archive and edition as securely differentiated categories. As readers we inhabit the same textual field as the approaches to documents and texts that we seek to define. To record is first to read and analyse sufficiently for the archival purpose; to interpret is first to ...
openaire   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Periodic impulsive fractional differential equations

open access: yesAdvances in Nonlinear Analysis, 2017
This paper deals with the existence of periodic solutions of fractional differential equations with periodic impulses. The first part of the paper is devoted to the uniqueness, existence and asymptotic stability results for periodic solutions of ...
Fečkan Michal, Wang Jin Rong
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Existence of solutions to differential inclusions with fractional order and impulses

open access: yesElectronic Journal of Differential Equations, 2010
We establish sufficient conditions for the existence of solutions for a class of initial value problem for impulsive fractional differential inclusions involving the Caputo fractional derivative.
Mouffak Benchohra   +3 more
doaj  

On the Global Practical Exponential Stability of h-Manifolds for Impulsive Reaction–Diffusion Cohen–Grossberg Neural Networks with Time-Varying Delays

open access: yesEntropy
In this paper, we focus on h-manifolds related to impulsive reaction–diffusion Cohen–Grossberg neural networks with time-varying delays. By constructing a new Lyapunov-type function and a comparison principle, sufficient conditions that guarantee the ...
Gani Stamov   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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