Results 51 to 60 of about 91,295 (314)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Impulsive boundary value problems for nonlinear implicit Caputo-exponential type fractional differential equations

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2020
This paper deals with existence and uniqueness of solutions to a class of impulsive boundary value problem for nonlinear implicit fractional differential equations involving the Caputo-exponential fractional derivative. The existence results are based on
Ahmed Malti   +3 more
doaj   +1 more source

Stability Analysis for a Class of Stochastic Differential Equations with Impulses

open access: yesMathematics, 2023
This paper is concerned with the problem of asymptotic stability for a class of stochastic differential equations with impulsive effects. A sufficient criterion on asymptotic stability is derived for such impulsive stochastic differential equations via ...
Mingli Xia   +3 more
doaj   +1 more source

Oscillation Caused By Impulses

open access: yes, 2001
The present paper is devoted to the investigation of the oscillation of a kind of very extensively studied second order nonlinear delay differential equations with impulses, some interesting results are obtained, which illustrate that impulses play a ...
Peng, Mingshu
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Bifurcation Analysis and Application for Impulsive Systems with Delayed Impulses [PDF]

open access: yesInternational Journal of Bifurcation and Chaos, 2017
In this article, we present a systematic approach to bifurcation analysis of impulsive systems with autonomous or periodic right-hand sides that may exhibit delayed impulse terms. Methods include Lyapunov–Schmidt reduction and center manifold reduction.
Kevin E. M. Church, Xinzhi Liu
openaire   +3 more sources

Reinforcement learning links spontaneous cortical dopamine impulses to reward [PDF]

open access: yes, 2021
In their pioneering study on dopamine release, Romo and Schultz speculated “…that the amount of dopamine released by unmodulated spontaneous impulse activity exerts a tonic, permissive influence on neuronal processes more actively engaged in preparation ...
Wang, Jing W.   +8 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Impulsivity and Decision Making [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 2005
The purpose of the present study was to explore the links among the four facets of impulsivity (urgency, lack of premeditation, lack of perseverance, and sensation seeking) proposed by and decision-making processes. Thirty undergraduate students completed a self-report questionnaire evaluating impulsivity as well as a task measuring decision-making ...
Zermatten, Ariane   +4 more
openaire   +4 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy