Results 261 to 270 of about 264,997 (335)

Job Precarity and Attitudes Towards Labour Unions: The Mitigating Role of Immigrant Background

open access: yesBritish Journal of Industrial Relations, EarlyView.
ABSTRACT Despite their significant and growing role in the European workforce, to date, little research attention has been paid to immigrant workers’ attitudes towards trade unions and provided mixed results. On the one hand, immigrants are expected to be more positive towards unions due to their lower economic capital and greater need for job ...
Anna‐Lena Nadler, Elif Naz Kayran
wiley   +1 more source

Divergence in μ and δ opioid receptor pharmacology in neurons and antinociceptive efficacy in neuropathic pain: Insights from MP135 and CYM51010

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and purpose Opioids targeting the μ opioid receptor remain largely ineffective in neuropathic pain conditions, emphasizing the need for novel therapeutic strategies. MP135 was reported to reduce thermal nociception in naive animals by activating μ‐δ opioid receptor heteromers.
Perrine Inquimbert   +13 more
wiley   +1 more source

Clinical Applications of Phosphoproteomics: Illuminating Cancer Signaling and Enabling Rational Therapeutic Strategies

open access: yesCancer Science, EarlyView.
Mass spectrometry‐based phosphoproteomics for mechanistic dissection of cancer signaling pathways and uncovering therapeutic vulnerabilities. ABSTRACT Protein phosphorylation is a central post‐translational modification regulating cellular signaling, frequently dysregulated in cancer.
Hirokazu Shoji   +2 more
wiley   +1 more source

Challenging the concept of functional high-risk myeloma through transcriptional and genetic profiling.

open access: yesBlood
Beer SA   +17 more
europepmc   +1 more source

Separation of PS diastereomers in GalNAc-conjugated siRNA-a comparative study of chromatographic and ion mobility mass spectrometry approaches. [PDF]

open access: yesAnal Bioanal Chem
Bill MK   +8 more
europepmc   +1 more source

Evolutionary divergence and functional insights into the heteromeric cis‐prenyltransferase of Paramecium tetraurelia

open access: yesThe FEBS Journal, EarlyView.
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk   +8 more
wiley   +1 more source

Patterns and Predictors of Steroid Use in a Real-World Inflammatory Bowel Disease Cohort. [PDF]

open access: yesJGH Open
Wu R   +8 more
europepmc   +1 more source

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