Results 31 to 40 of about 49,728 (257)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Journal of Medical Toxicology, 2011 The independent medical examination (IME) is a process that makes many fellows and medical toxicologists alike uncomfortable. Many of those who perform IMEs on a regular basis believe it is our responsibility as medical toxicologists to provide much needed expertise in this field. Additionally, as the tides carrying poison center and toxicology service
openaire +2 more sources
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
IMS: The New Generation of Internet-Protocol-Based Multimedia Services [PDF]
, 2013 Legacy networks, both fixed and mobile, which were originally designed for voice communications, are progressively migrating to new infrastructures that promise to revolutionize the services offered.
Camarillo, Gonzalo +4 more
core
Implementation of IMS Testbeds Using Open Source Platforms
Communications, 2012 The IP Multimedia Subsystem (IMS) is a control architecture framework for the Next Generation Network (NGN). It is expected that this new network architecture will provide a new kind of IP multimedia services delivered in network converged environments ...
Pavel Segec, Tatiana Kovacikova
doaj +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Improving the pedagogical expressiveness of IMS LD [PDF]
, 2009 The IMS Learning Design specification (LD) was introduced in order to describe any learning and teaching scenario in a formal way. Its high level of generality, however, may make it difficult for teachers and instructional designers to apply it to their ...
Gilbert, Lester, Sitthisak, Onjira
core
Contribution to the Management of Traffic in Networks
Advances in Electrical and Electronic Engineering, 2014 The paper deals with Admission control methods (AC) in IMS networks (IP multimedia subsystem) as one of the elements that help ensure QoS (Quality of service).
Filip Chamraz, Ivan Baronak
doaj +1 more source
Hadamard Transform Ion Mobility Spectrometry Based on Matrix Encoding Modulation
Sensors, 2023 Ion mobility spectrometry (IMS) has been widely used for the on-site detection of trace chemicals, but continue to suffer from a low duty cycle of ion injection.
Ke Chen, Lingfeng Li, Peng Li
doaj +1 more source
Microstructure Evolution of a VMnFeCoNi High‐Entropy Alloy After Synthesis, Swaging, and Annealing
Advanced Engineering Materials, EarlyView.The synthesis and processing (rotary swaging and annealing) of the novel VMnFeCoNi alloy is investigated, alongside the estimation of the grain size effect on hardness. Analysis of a wide grain size range of recrystallized microstructures (12–210 µm) reveals a low annealing twin density.
Aditya Srinivasan Tirunilai +6 more
wiley +1 more source