Results 11 to 20 of about 475,711 (295)
The cell biology of touch [PDF]
Journal of Cell Biology, 2010 The sense of touch detects forces that bombard the body’s surface. In metazoans, an assortment of morphologically and functionally distinct mechanosensory cell types are tuned to selectively respond to diverse mechanical stimuli, such as vibration, stretch, and pressure.
Lumpkin, Ellen A. +2 more
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Exploratory cell dynamics: a sense of touch for cells? [PDF]
Biological Chemistry, 2018 Abstract Cells need to process multifaceted external cues to steer their dynamic behavior. To efficiently perform this task, cells implement several exploratory mechanisms to actively sample their environment. In particular, cells can use exploratory actin-based cell protrusions and contractions to engage and squeeze the environment and ...
Nalbant, Perihan, Dehmelt, Leif
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Merkel cells and neurons keep in touch [PDF]
Trends in Cell Biology, 2015 The Merkel cell-neurite complex is a unique vertebrate touch receptor comprising two distinct cell types in the skin. Its presence in touch-sensitive skin areas was recognized more than a century ago, but the functions of each cell type in sensory transduction have been unclear.
Seung-Hyun, Woo +2 more
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Organogenesis: keeping in touch with the germ cells [PDF]
Current Biology, 2003 DE-cadherin and its novel regulator, the transmembrane protein Fear of Intimacy, have been found to control the adhesive interactions between germline and somatic cells that lead to gonad formation in Drosophila.
Godt, Dorothea, Tepass, Ulrich
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Cadherin signaling: keeping cells in touch [PDF]
F1000Research, 2015 Cadherin-catenin complexes are critical for the assembly of cell-cell adhesion structures known as adherens junctions. In addition to the mechanical linkage of neighboring cells to each other, these cell-cell adhesion protein complexes have recently emerged as important sensors and transmitters of the extracellular cues inside the cell body and into ...
Olga Klezovitch, Valeri Vasioukhin
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Functional expression of TRPV4 channels in human collecting duct cells: implications for secondary hypertension in diabetic nephropathy [PDF]
, 2012 Background. The Vanilloid subfamily of transient receptor potential (TRPV) ion channels has been widely implicated in detecting osmotic and mechanical stress.
Bland, Rosemary +2 more
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The cellular basis of mechanosensory Merkel-cell innervation during development
eLife, 2019 Touch sensation is initiated by mechanosensory neurons that innervate distinct skin structures; however, little is known about how these neurons are patterned during mammalian skin development.
Blair A Jenkins +4 more
doaj +1 more source
Ammonia toxicity: from head to toe? [PDF]
, 2016 Ammonia is diffused and transported across all plasma membranes. This entails that hyperammonemia leads to an increase in ammonia in all organs and tissues.
Dasarathy, Srinivasan +6 more
core +1 more source
A Cascade of Wnt, Eda, and Shh Signaling Is Essential for Touch Dome Merkel Cell Development.
PLoS Genetics, 2016 The Sonic hedgehog (Shh) signaling pathway regulates developmental, homeostatic, and repair processes throughout the body. In the skin, touch domes develop in tandem with primary hair follicles and contain sensory Merkel cells.
Ying Xiao +8 more
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Scientific Reports, 2023 At a crime scene, investigators are faced with a multitude of traces. Among them, biological traces are of primary interest for the rapid genetic-based identification of individuals.
Mathilde Recipon +8 more
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