Results 61 to 70 of about 274,248 (306)

Therapeutic Hypothermia after In-Hospital Cardiac Arrest in Children

New England Journal of Medicine, 2017
Background Targeted temperature management is recommended for comatose adults and children after out‐of‐hospital cardiac arrest; however, data on temperature management after in‐hospital cardiac arrest are limited.
F. Moler, Faye S. Silverstein, R. Holubkov, B. Slomine, J. Christensen, Vinay M. Nadkarni, K. Meert, B. Browning, Victoria L. Pemberton, K. Page, M. Gildea, B. Scholefield, S. Shankaran, Jamie S. Hutchison, John T. Berger, G. Ofori-Amanfo, C. Newth, A. Topjian, Kimberly S. Bennett, J. Koch, Nga Pham, N. Chanani, Jose A. Pineda, R. Harrison, H. Dalton, J. Alten, C. Schleien, Denise M. Goodman, Jerry J. Zimmerman, U. Bhalala, A. Schwarz, M. Porter, Samir Shah, E. Fink, P. McQuillen, Theodore Wu, S. Skellett, Neal J. Thomas, J. Nowak, Paul B. Baines, J. Pappachan, Mudit Mathur, E. Lloyd, É. W. van der Jagt, E. Dobyns, Michael T. Meyer, Ronald C. Sanders, A. Clark, J. Dean   +48 more
semanticscholar   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Positive neurologic outcome in a child after in-hospital cardiac arrest

Zaporožskij Medicinskij Žurnal, 2019
The case of positive neurologic outcome in a child after in-hospital cardiac arrest is presented in the article. Factors influencing the survival and neurologic outcome following CPR in children are analysed.
L. D. Tantsiura, I. V. Kyselova, A. V. Biliaiev, V. V. Orel, M. V. Trykash, V. M. Skliar, I. M. Kolosova   +6 more
doaj   +1 more source

Survival and long-term outcomes following in-hospital cardiac arrest in a Swiss university hospital: a prospective observational study

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2021
Background Incidence of in-hospital cardiac arrest is reported to be 0.8 to 4.6 per 1,000 patient admissions. Patient survival to hospital discharge with favourable functional and neurological status is around 21–30%.
Alexander Fuchs, Dominic Käser, Lorenz Theiler, Robert Greif, Jürgen Knapp, Joana Berger-Estilita   +5 more
doaj   +1 more source

Early Outcomes of Out-of-Hospital Cardiac Arrest after Early Defibrillation: a 24 Months Retrospective Analysis [PDF]

, 2006
Introduction: Cardiovascular disease remains the most common cause of death in the United States and most other Western nations. Among these deaths, sudden, out-of-hospital cardiac arrest claims approximately 1000 lives each day in the United States ...
Barbara Severgnini, Enrico Maria Greco, Paolo Terranova, Paolo Valli, Simonetta Dell'Orto   +4 more
core   +1 more source

One-year survival after in-hospital cardiac arrest: A systematic review and meta-analysis.

Resuscitation, 2018
INTRODUCTION In-hospital cardiac arrest is a major adverse event with an incidence of 1-6/1000 admissions. It has been poorly researched and data on survival is limited.
M. Schluep, B. Gravesteijn, R. Stolker, H. Endeman, S. Hoeks   +4 more
semanticscholar   +1 more source

Pediatric In-Hospital Cardiac Arrest and Cardiopulmonary Resuscitation in the United States

JAMA pediatrics, 2020
IMPORTANCE Pediatric in-hospital cardiac arrest (IHCA) occurs frequently and is associated with high morbidity and mortality. The objective of this narrative review is to summarize the current knowledge and recommendations regarding pediatric IHCA and ...
R. Morgan, M. Kirschen, T. Kilbaugh, R. Sutton, Alexis A. Topjian   +4 more
semanticscholar   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Risk factors and outcome of extracorporeal cardiopulmonary resuscitation patients with out-of-hospital cardiac arrest and in-hospital cardiac arrest: a nationwide prospective and observational study of 939 hospitals in China

BMC Emergency Medicine
Background Sudden cardiac arrest represents a global health challenge characterized by high mortality and morbidity rates. Extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly considered as an effective treatment for cardiac arrest ...
Di Shi, Bo Li, Wei Pan, Fuping Guo, Hui Jiang, Liu Chengxi, Huadong Zhu, Jihai Liu, Jieqing Chen, Liang Zong, Xiao Song, Chen Lin, Xin Ding, Xiang Zhou, Chang Yin, Bin Du, on behalf of the China National Critical Care Quality Control Center-the ECMO quality improvement action (EQIA) study   +16 more
doaj   +1 more source

Early changes in hospital resuscitation practices during the COVID-19 pandemic

Resuscitation Plus, 2022
Background: The coronavirus disease 2019 (COVID-19) pandemic resulted in many disruptions in care for patients experiencing in-hospital cardiac arrest (IHCA).
Kayla M. Secrest, Theresa M. Anderson, Brad Trumpower, Molly Harrod, Sarah L. Krein, Timothy C. Guetterman, Paul S. Chan, Brahmajee K. Nallamothu   +7 more
doaj   +1 more source