Results 71 to 80 of about 274,248 (306)

The association between hemoglobin concentration and neurologic outcome after cardiac arrest. [PDF]

, 2016
PURPOSE: The purpose of the study is to determine the association between hemoglobin concentration (Hgb) and neurologic outcome in postarrest patients. METHODS: We conducted a retrospective cohort study using the Penn Alliance for Therapeutic Hypothermia
Dodampahala, Kalani, Gaieski, David F., Goyal, Munish, Grossestreuer, Anne V., Johnson, Nicholas J., Perman, Sarah M., Rosselot, Babette   +6 more
core   +1 more source

Mild hypothermia during advanced life support: a preliminary study in out-of-hospital cardiac arrest [PDF]

, 2008
INTRODUCTION: Induction of mild hypothermia after cardiac arrest may confer neuroprotection. We assessed the feasibility, safety and effectiveness of therapeutic infusion of 2 l of normal saline at 4 degrees C before return of spontaneous circulation ...
Cedric Bruel, Jean-Jacques Parienti, William Marie, Xavier Arrot, Cedric Daubin, Damien Du Cheyron, Massimo Massetti, Pierre Charbonneau   +7 more
core   +1 more source

Clinical Outcomes of In-Hospital Cardiac Arrest in COVID-19.

JAMA Internal Medicine, 2020
This case series examines outcomes of in-hospital cardiac arrest among patients with COVID-19.
Shrinjaya B Thapa, T. Kakar, C. Mayer, Dilip Khanal   +3 more
semanticscholar   +1 more source

Effect of Lower vs Higher Oxygen Saturation Targets on Survival to Hospital Discharge Among Patients Resuscitated After Out-of-Hospital Cardiac Arrest: The EXACT Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2022
Importance The administration of a high fraction of oxygen following return of spontaneous circulation in out-of-hospital cardiac arrest may increase reperfusion brain injury.
S. Bernard, J. Bray, Karen Smith, M. Stephenson, J. Finn, Hugh J. M. Grantham, Cindy Hein, Stacey Masters, D. Stub, G. Perkins, Natasha Dodge, Catherine Martin, S. Hopkins, P. Cameron   +13 more
semanticscholar   +1 more source

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source

Factors associated with post-arrest withdrawal of life-sustaining therapy. [PDF]

, 2017
INTRODUCTION: Most successfully resuscitated cardiac arrest patients do not survive to hospital discharge. Many have withdrawal of life sustaining therapy (WLST) as a result of the perception of poor neurologic prognosis.
Abella, Benjamin S., Gaieski, David F., Grossestreuer, Anne V., Haukoos, Jason S., Ikeda, Daniel J., Moskowitz, Ari, Perman, Sarah M., Wiebe, Douglas J.   +7 more
core   +1 more source

Out-of-hospital therapeutic hypothermia in cardiac arrest victims [PDF]

, 2009
Despite many years of research, outcome after cardiac arrest is dismal. Since 2005, the European Resuscitation Council recommends in its guidelines the use of mild therapeutic hypothermia (32-34°) for 12 to 24 hours in patients successfully resuscitated ...
Wilhelm Behringer, Jasmin Arrich, Michael Holzer, Fritz Sterz   +3 more
core   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce, Goknur Selen Kocak, José Verdú‐Díaz, Jorge Alonso‐Pérez, Kristl G. Claeys, Tanya Stojkovic, Gorka Fernández‐Eulate, Pascal Laforêt, Najoua Miladi, Filipe Di Pace, Cristiane Araujo Martins Moreno, Edmar Zanoteli, Conrad C. Weihl, Volker Straub, Ana Töpf, Jordi Díaz‐Manera, Sarcoglycan European Cohort Consortium, Adele D′Amico, Adolfo López de Munain, Alicia Alonso‐Jiménez, Ana Camacho‐Salas, Andrea Gangfuß, Andrés Nascimento, Anna Sarkozy, Anneke J. van der Kooi, Arturo Fraga‐Bau, Béla Melegh, Benedikt Schoser, Bjarne Udd, Blaz Koritnik, Carlos Ortez, Chiara Marini Bettolo, Chiara Panicucci, Claudia Weiss, Claudio Bruno, Claudio Semplicini, Cristina Dominguez‐González, Cristina Garrido, David Gómez‐Andrés, Edoardo Malfatti, Elena Pegoraro, Elke De Vos, Francina Munell, Gabriele Dekomien, Giacomo Pietro Comi, Giorgio Tasca, Isabelle Richard, Jan L. De Bleecker, Jana Haberlová, Jesper Helbo Storgaard, Johanna Palmio, John Vissing, Juan Carlos de Leon‐Hernández, Kinga Hadzsiev, Laura Costa‐Comellas, Lea Leonardis, Leroy ten Dam, Lidia González‐Quereda, Luca Bello, Luisa Politano, Manuela Santos, Marianne de Visser, Marie Rohlenová, Matteo Garibaldi, Michela Guglieri, Nicolas Deconinck, Nicoline Løkken, Omar Abdel‐Mannan, Pia Gallano, Roberto Fernández‐Torrón, Ulrike Schara‐Schmidt, Vincenzo Nigro, Vittoria Zangaro   +72 more
wiley   +1 more source

A Multicenter Evaluation of Survival After In-Hospital Cardiac Arrest in Coronavirus Disease 2019 Patients

Critical Care Explorations, 2021
IMPORTANCE:. In-hospital cardiac arrest survival among coronavirus disease 2019 patients has been reported to range from 0% to 12%. These numbers are significantly lower than reported prepandemic in-hospital cardiac arrest survival rates of approximately
Abhishek Bhardwaj, MD, FACP, Mahmoud Alwakeel, MD, Talha Saleem, MD, Saira Afzal, MD, Sura Alqaisi, MD, Aisha R. Saand, MD, Hanan Al. Najjar, MD, Lori Griffiths, RN, MPH, Xiaozhen Han, MS, Xiaofeng Wang, PhD, Silvia Perez-Protto, MD, MS, FCCM, Benjamin S. Abella, MD, MPhil, FAHA, FACEP, David F. Gaieski, MD, FACEP, FCCM, Abhijit Duggal, MD, MPH, MSc, Francois Abi Fadel, MD, FACP, FCCP   +14 more
doaj   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source