Results 161 to 170 of about 1,063,217 (316)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

State of the Art in Parallel Computing with R

open access: yes
R is a mature open-source programming language for statistical computing and graphics. Many areas of statistical research are experiencing rapid growth in the size of data sets. Methodological advances drive increased use of simulations.
Hao Yu   +5 more
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

The Computer Science Network.

open access: yesAI Mag., 1982
The CSNET project, sponsored by the National Science Foundation, has as its goal the design and implementation of a computer communications network to provide services to computer science research groups in the United States. Experience with Arpanet has shown that access to a computer network can lead to significantly higher level of interaction ...
openaire   +2 more sources

FPGAs Are the Hero In-Network Computing Needs

open access: yes
In-network computing has gained some traction recently with the advent of programmable switches in the datacenter, however, for widespread adoption as a general computing paradigm, more flexible deployment platforms are required.
István, Zsolt   +5 more
core   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Social Network Analysis with sna

open access: yes
Modern social network analysis---the analysis of relational data arising from social systems---is a computationally intensive area of research. Here, we provide an overview of a software package which provides support for a range of network analytic ...
Carter T. Butts
core  

Computing resources sensitive parallelization of neural neworks for large scale diabetes data modelling, diagnosis and prediction

open access: yes, 2011
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Diabetes has become one of the most severe deceases due to an increasing number of diabetes patients globally.
Qi, Hao
core  

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