Results 81 to 90 of about 65,675 (252)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

A computational model for a molecular chemical sensor

Nanoscale
In this study, we propose that a molecular junction with a sharp Negative Differential Resistance (NDR) current peak could improve the selectivity, thereby functioning as a potential molecular sensor for molecule recognition.
Mengxuan Li, Clotilde S. Cucinotta, Andrew P. Horsfield   +2 more
openaire   +3 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Haptic In‐Sensor Computing Device Based on CNT/PDMS Nanocomposite Physical Reservoir

Advanced Intelligent Systems
The importance of haptic in‐sensor computing devices has been increasing. Herein, a haptic sensor with a hierarchical structure is successfully fabricated via the sacrificial template method, using carbon nanotube‐polydimethylsiloxane (CNT‐PDMS ...
Kouki Kimizuka, Saman Azhari, Shoshi Tokuno, Ahmet Karacali, Yuki Usami, Shuhei Ikemoto, Hakaru Tamukoh, Hirofumi Tanaka   +7 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

MXene-Ti3C2Tx-Based Neuromorphic Computing: Physical Mechanisms, Performance Enhancement, and Cutting-Edge Computing

Nano-Micro Letters
Highlights This review reveals the advantages of MXene-Ti3C2Tx for neuromorphic devices, classifies the core physical mechanisms, and outlines strategies to drive targeted optimization and future innovation.
Kaiyang Wang, Shuhui Ren, Yunfang Jia, Xiaobing Yan, Lizhen Wang, Yubo Fan   +5 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Modeling and Analysis on Congestion Control for Data Transmission in Sensor Clouds

International Journal of Distributed Sensor Networks, 2014
Wireless Sensor Networks (WSNs) and Cloud computing are two emerging technologies, respectively, in the networking and computing fields. Sensor Cloud integrates WSNs and Clouds into an extended form of cloud infrastructure that manages sensors scattered ...
Jun Huang, Donggai Du, Qiang Duan, Yanguang Zhang, Yanxiao Zhao, Hongshan Luo, Zhuoqi Mai, Qian Liu   +7 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source