Results 31 to 40 of about 423,593 (300)

Numerical study on thermal-hydraulics of external reactor vessel cooling in high-power reactor using MARS-KS1.5 code: CFD-aided estimation of natural circulation flow rate

open access: yesNuclear Engineering and Technology, 2022
This paper presents a numerical investigation of two-phase natural circulation flows established when external reactor vessel cooling is applied to a severe accident of the APR1400 reactor for the in-vessel retention of the core melt.
Min Seop Song   +3 more
doaj   +1 more source

Fuel–Coolant Interaction Visualization Test for In-Vessel Corium Retention External Reactor Vessel Cooling (IVR-ERVC) Condition

open access: yesNuclear Engineering and Technology, 2016
A visualization test of the fuel–coolant interaction in the Test for Real cOrium Interaction with water (TROI) test facility was carried out. To experimentally simulate the In-Vessel corium Retention (IVR)- External Reactor Vessel Cooling (ERVC ...
Young Su Na   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Preliminary Study on Core Melt In-vessel Retention of Pool-type Sodium-cooled Fast Reactor

open access: yesYuanzineng kexue jishu
The inherent safety of reactor is emphasized in the design of the sodium-cooled fast reactors (SFRs). For accident mitigation, inherent safety and passive measures are adopted to reduce the demand for power sources and enhance safety and economy.
XUE Fangyuan1, ZHANG Donghui2, LIU Yizhe1, ZHANG Xisi1
doaj   +1 more source

The Dutch Law Perspective on the Enforcement of Marina Operator Claims

open access: yesPoredbeno Pomorsko Pravo, 2019
This article focuses on a very specific aspect of maritime law, i.e. the remedies that exist under Dutch law in order for a marina operator to pursue a claim against a vessel owner either based on a contract or based on torts.
Vivian van der Kuil
doaj   +1 more source

Experiments on interactions of molten steel with suboxidized corium crust for in-vessel melt retention

open access: yes, 2019
International audienceIn the framework of the European IVMR project, dedicated to the assessment of In-Vessel Retention (IVR) strategy for high power reactors, VITI-CORMET tests, performed in VITI facility (CEA-Cadarache/PLINIUS Severe Accident Platform),
Fouquart, Pascal   +5 more
core   +1 more source

Numerical simulations of the Rayleigh-Bénard-Marangoni convections in a thin metallic laye

open access: yes, 2021
International audienceWithin the context of nuclear power safety, the In-Vessel Retention (IVR) strategy consists in sustaining the integrity of the reactor pressure vessel by External Reactor Vessel Cooling (ERVC).
Dang, Chunhui   +3 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

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