Results 71 to 80 of about 120,147,709 (302)
Effects of strychnopentamine on cells cultured in vitro
Chemico-Biological Interactions, 1991 This paper describes the powerful cytotoxic action exerted by strychnopentamine (SP), a dimeric indole alkaloid extracted from Strychnos usambarensis Gilg, on B16 melanoma cells and on non-cancer human fibroblasts cultured in vitro. SP strongly inhibits cell proliferation and induces cell death at a relatively low concentration (less than 1 microgram ...
Quetin-Leclercq, J. +3 more
openaire +3 more sources
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
IN VITRO VALIDATION OF A NOVEL BICOMPARTMENTAL CULTURE SYSTEM.
, 2019 In vitro cell/tissue culture represents a widespread methodology to investigate pathophysiology with good cost/benefit ratio, in compliance with the 3R principles. Cell differentiation, co-culture, conditioning under perfusion and recover/reuse are among
M. Soncini +3 more
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cAMP and cGMP enhance hepatocyte DNA synthesis in vitro
, 1974 cAMP and cGMP enhance neonatal rat hepatocytes' DNA synthesis in in vitro primary ...
V. MENEGHELLI +3 more
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Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
IN VITRO CULTURE OF CORIANDRUM SATIVUM L.
Acta Horticulturae, 2011 Coriander (coriandrum sativumL.) is a plant from the Umbellifera family. In Portugal, the use of coriander plants in gastronomy is very common, like in all the countries in the Mediterranean area. This plant species has also several other applications than as an aromatic plant, such as medicinal, being recommended for dyspeptic complaints, loss of ...
Dias, Maria Inês +3 more
openaire +2 more sources
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Seed and Seedling Surface-Sterilization for In Vitro Culture of Tillandsia gardneri (Bromeliaceae)
, 2012 Tillandsia gardneri is a bromeliad with ornamental value and a wide geographical distribution over Brazil. However, due to habitat loss and illegal over-collection in the wild it is included as a vulnerable species in the official list of endangered ...
Dematte, M. E. S. P. [UNESP] +4 more
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Response of arum lily calli to culture filtrate of Pectobacterium carotovorum subsp. carotovorum [PDF]
, 2009 This report demonstrated that culture filtrate of Pectobacterium carotovorum ssp. carotovorum isolate ZT0505, the pathogen of bacterial soft rot disease of arum lily (Zantedeschia sp.), contained extracellular enzymes and caused arum lily leaf tissue and
Custers, J.B.M. +4 more
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