Results 81 to 90 of about 120,147,709 (302)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Optimization of in vitro culture of honeybee nervous tissue for pesticide risk assessment
, 2022 The most used pesticides have neurotoxic action on the neurotransmitter system of target and non-targeted insects, such as honeybees. However, honeybees have foremost importance worldwide, which has encouraged the development of tools to evaluate the ...
de Alencar, Luciano Delmondes +17 more
core +1 more source
, 2018 The effects of micro and nanoparticles on the innate immune system have been widely investigated and a general lack of agreement between in vivo and in vitro assays has been observed.
Häcker, U. +18 more
core +2 more sources
FSH and LH Secretion from in-vitro Cultured Buffalo Anterior Pituitary Cells Following Treatment with Diethyl-Stilbestrol and Medroxy-Progesterone and Their Effects on Ovarian Activity and Hematological Variables of Female Rabbits [PDF]
Pakistan Veterinary Journal, 2016 Aims of this study were: to investigate whether FSH and LH secretion from in-vitro cultured buffalo adenohypophyseal cells can be increased by supplementing culture media with diethyl-stilbestrol and medroxy-progesterone, respectively; to monitor ...
Kaleem Iqbal1, Nafees Akhtar1*, Nazir Ahmad1 and Sajjad-ur-Rahman2
doaj
Revista Brasileira de Fruticultura, 2008 A conservação de borbulhas de citros permite ao viveirista um melhor planejamento no seu viveiro. Porém, os testes usados para comprovar a viabilidade das borbulhas, consistem na enxertia das mesmas em porta-enxertos, que sofrem influência de vários ...
Hardi Schmatz Maciel +2 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Revista Colombiana de Biotecnología, 2010 En este trabajo de investigación se propagaron, bajo condiciones in vitro, propágulos de Marchantia polymorpha evaluando su desarrollo vegetativo mediante observaciones y registros semanales a cada cultivo por tratamiento en función del tiempo de ...
Jaime Alonso Pedroza-Manrique +1 more
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In vitro developmental competence of prepubertal goat oocytes cultured with recombinant activin-A
Animal, 2014 The present study was designed to evaluate the effect of activin-A during the in vitro oocyte maturation (IVM) and in vitro embryo culture (IVC) on nuclear maturation, blastocyst yield and blastocyst quality of prepubertal goat oocytes.
S. Hammami +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
In vitro soil-less (IVS) rooting medium [PDF]
, 2006 The principle hypothesis of this thesis is that hypoxia, in agar-based media, compromises rooting in vitro. From a practical point of view this is important because most plant tissue culture activities require the material to be successfully acclimatised
Newell, Christopher Jack
core