Results 41 to 50 of about 2,462,234 (268)

Aortic Slimgraft: Ex vivo and in vivo study [PDF]

Journal of Vascular Surgery, 2001
In this article we describe a method for assembling an endovascular graft within the aorta with a graft and then a stent introduced sequentially over a guidewire as separate components. In the ex vivo study, an endovascular graft that was 25 mm in diameter was introduced through a 9F introducer.
Kerr, Andrew S., Osende, Julio, Fallon, John T., Badimon, Juan   +3 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Limitations of ex vivo measurements for in vivo neuroscience [PDF]

Proceedings of the National Academy of Sciences, 2017
Significance Understanding the physiology of noninvasive brain stimulation requires precise knowledge of biophysical properties of brain tissue (e.g., conductivities). Numerous researchers have tried to measure these properties using in vitro, in vivo, and ex vivo preparations in nonhuman animals or human tissue, though findings have ...
Alexander, Opitz, Arnaud, Falchier, Gary S, Linn, Michael P, Milham, Charles E, Schroeder   +4 more
openaire   +2 more sources

In Vitro, Ex Vivo, and In Vivo Models for the Study of Pemphigus

International Journal of Molecular Sciences, 2022
Pemphigus is a life-threatening autoimmune disease. Several phenotypic variants are part of this family of bullous disorders. The disease is mainly mediated by pathogenic autoantibodies, but is also directed against two desmosomal adhesion proteins, desmoglein 1 (DSG1) and 3 (DSG3), which are expressed in the skin and mucosae.
Roberta Lotti, Claudio Giacinto Atene, Emma Dorotea Zanfi, Matteo Bertesi, Tommaso Zanocco-Marani   +4 more
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Human Neural Stem Cell Induced Functional Network Stabilization After Cortical Stroke: A Longitudinal Resting-State fMRI Study in Mice

Frontiers in Cellular Neuroscience, 2020
Most stroke studies dealing with functional deficits and assessing stem cell therapy produce extensive hemispheric damage and can be seen as a model for severe clinical strokes.
Anuka Minassian, Claudia Green, Michael Diedenhofen, Stefanie Vogel, Simon Hess, Simon Hess, Maren Stoeber, Marina Dobrivojevic Radmilovic, Marina Dobrivojevic Radmilovic, Dirk Wiedermann, Peter Kloppenburg, Peter Kloppenburg, Mathias Hoehn, Mathias Hoehn   +13 more
doaj   +1 more source

The VIVO project

, 2022
The VIVO project is presented as a worldwide network of open source systems for research information management.
openaire   +2 more sources

Desmosomes In Vivo [PDF]

Dermatology Research and Practice, 2010
The structure, function, and regulation of desmosomal adhesion in vivo are discussed. Most desmosomes in tissues exhibit calcium‐independent adhesion, which is strongly adhesive or “hyperadhesive”. This is fundamental to tissue strength. Almost all studies in culture are done on weakly adhesive, calcium‐dependent desmosomes, although hyperadhesion can ...
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source