Results 91 to 100 of about 700,727 (353)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
In vitro and in vivo evaluation of cephalosporins for the treatment of Lyme disease. [PDF]
, 2018 BackgroundLyme disease accounts for >90% of all vector-borne disease cases in the United States and affect ~300,000 persons annually in North America.
Ambati, Aditya +9 more
core
SUSY in Silico: numerical D-brane bound state spectroscopy [PDF]
, 2016 We numerically construct the BPS and non-BPS wavefunctions of an $\mathcal{N}=4$ quiver quantum mechanics with two Abelian nodes and a single arrow. This model captures the dynamics of a pair of wrapped D-branes interacting via a single light string mode.
Anous, Tarek
core +2 more sources
Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz +11 more
wiley +1 more source
A longitudinal MRI dataset of brain metastases with tumor segmentations, clinical & radiomic data
Scientific DataBrain metastases (BM) are a severe complication of multiple primary malignancies and constitute the most frequent tumors of the central nervous system.
Dimitra Flouri +9 more
doaj +1 more source
In Silico Classification of Industrial Chemicals Associated with Acute Aquatic Toxic Action Utilising Molecular Initiating Events [PDF]
, 2021 Maria Sapounidou
openalex +1 more source
Kernel methods for in silico chemogenomics
, 2007 Predicting interactions between small molecules and proteins is a crucial ingredient of the drug discovery process. In particular, accurate predictive models are increasingly used to preselect potential lead compounds from large molecule databases, or to
Jacob, Laurent, Vert, Jean-Philippe
core +1 more source
Combining in silico prediction and ribosome profiling in a genome-wide search for novel putatively coding sORFs [PDF]
, 2013 Background: It was long assumed that proteins are at least 100 amino acids (AAs) long. Moreover, the detection of short translation products (e. g.
Baggerman, Geert +6 more
core +2 more sources
TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara +18 more
wiley +1 more source