Results 71 to 80 of about 423,064 (316)
Numerical simulation of waste landfill biodegradation: Fitting experimental data
DynaLandfill remains economically viable for the disposal of Municipal Solid Waste (MSW), however, experiences of failure in several Colombian and global locations, lead to soil, water, and air pollution, harming ecosystems, and biodiversity.
Vladimir Buelvas-Hernandez +2 more
doaj +1 more source
In silico toxicology protocols
Regulatory Toxicology and Pharmacology, 2018 The present publication surveys several applications of in silico (i.e., computational) toxicology approaches across different industries and institutions. It highlights the need to develop standardized protocols when conducting toxicity-related predictions.
Myatt, Glenn J. +83 more
openaire +2 more sources
In Silico Transitions to Multicellularity [PDF]
, 2015 The emergence of multicellularity and developmental programs are among the major problems of evolutionary biology. Traditionally, research in this area has been based on the combination of data analysis and experimental work on one hand and theoretical approximations on the other.
Solé, Ricard V., Duran-Nebreda, Salva
openaire +2 more sources
The in silico human surfaceome [PDF]
Proceedings of the National Academy of Sciences, 2018 Significance Despite the fundamental importance of the surfaceome as a signaling gateway to the cellular microenvironment, it remains difficult to determine which proteoforms reside in the plasma membrane and how they interact to enable context-dependent signaling functions.
Damaris Bausch-Fluck +6 more
openaire +3 more sources
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Improving route development using convergent retrosynthesis planning
Journal of CheminformaticsRetrosynthesis consists of recursively breaking down a target molecule to produce a synthesis route composed of readily accessible building blocks. In recent years, computer-aided synthesis planning methods have allowed a greater exploration of potential
Paula Torren-Peraire +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
, 2022 This repository contains the parameter sets of the population of TorORd models and the the population of ORdmD models, the ORdmD CellML file and MALTAB code used in Llopis-Lorente, J., Trenor, B., Saiz, J. (2022).
Trenor Gomis, Beatriz Ana +2 more
core
In silico evolution of diauxic growth [PDF]
, 2015 The glucose effect is a well known phenomenon whereby cells, when presented with two different nutrients, show a diauxic growth pattern, i.e. an episode of exponential growth followed by a lag phase of reduced growth followed by a second phase of ...
Dominique F. Chu, Chu, Dominique
core +1 more source
Optimization of an in silico protocol to characterize membrane PAINS
, 2021 Membrane Pan-Assay INterference compoundS (PAINS) are a class of molecules that interact non-specifically with lipid bilayers and alter their physicochemical properties.
Pedro B. P. S., Reis +4 more
core +1 more source