Results 201 to 210 of about 700,727 (353)

Conceptual and organizational barriers to quantitative systems pharmacology modeling of pathophysiological systemic drug hypotheses

CPT: Pharmacometrics & Systems Pharmacology, 2022
Ronald Gieschke, Robert Carr
doaj   +1 more source

Modernising antiviral drug discovery: harnessing medicinal plants through machine learning and metabolomics to target the SARS-CoV-2 main protease. [PDF]

In Silico Pharmacol
Msobo A, Maphari PW, Koorsen G, Singab ANB, Mhlongo MI.   +4 more
europepmc   +1 more source

In silico modelling of transporter-mediated xenobiotic flux through cells

, 2010
Samantha L. Forster
openalex   +1 more source

Detachment‐Induced FAK‐STAT3‐NNMT Inhibits CTCs Anoikis to Promote Breast Cancer Metastasis by Enhancing Fatty Acid Oxidation

Advanced Science, EarlyView.
The FAK‐STAT3‐NNMT axis drives anoikis resistance in circulating tumor cells by reprogramming fatty acid oxidation. Targeting this metabolic vulnerability suppresses metastasis, untangling a key mechanism of breast cancer progression and revealing NNMT as a promising therapeutic target.
Qingchao Tong, Yilei Ma, Yuzhen Gao, Lin Zhou, Luping Lou, Qiang Fang, Sining Fang, Ru Zhao, Jin Zeng, Jun Yang, Guoli Li, Xinyou Xie, Yanzhong Wang, Jun Zhang   +13 more
wiley   +1 more source

Measurable Feature Prediction for Estimating Chemical Space Coverage in LC-ESI-HRMS Nontargeted Analysis. [PDF]

Anal Chem
Renai L, Turkina V, Chojnacka A, Gargano AFG, Samanipour S.   +4 more
europepmc   +1 more source

A Holistic In Silico Approach to Find Novel Inhibitors for Erbb1 and Erbb2 Kinases

, 2016
Jian Bin Hu, Ming Jun Dong
openalex   +1 more source

In silico Study of Pyrano [2,3-C] Pyrazoles Derivatives as Selective Serotonin Reuptake Inhibitiors

, 2021
Bais Abhinav
openalex   +1 more source

Mass‐Produced and High‐Performance Nanowell Biosensor Fabricated via Semiconductor Manufacturing for Rapid and Accurate COVID‐19 Diagnosis in the Clinical Field

Advanced Science, EarlyView.
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park, Zahra Rezaei, Nam Ho Bae, Donggee Rho, Da‐Seul Kim, EunYoung Go, YoungTae Seo, Seok Jae Lee, Won Chan Seo, Luke P. Lee, HeaYeon Lee, Su Ryon Shin   +11 more
wiley   +1 more source

Interpreting circulating microbiome-related metabolites in coronary heart disease. [PDF]

PLoS Med
Sun Z, Shi M, Zheng Y.
europepmc   +1 more source

In Silico T Cell Epitope Identification for SARS-CoV-2: Progress and Perspectives

, 2020
Muhammad Saqib Sohail, Syed Faraz Ahmed, Ahmed Abdul Quadeer, Matthew R. McKay   +3 more
openalex   +1 more source