Results 251 to 260 of about 620,275 (284)
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Molecular Informatics, 2011
AbstractProtein‐protein interactions (PPIs) play a central and crucial role in almost every cellular process. Understanding the structural basis of protein‐protein interactions can lead to the development of new drugs for treatment of various diseases.
Matteo Floris, MORO, STEFANO
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AbstractProtein‐protein interactions (PPIs) play a central and crucial role in almost every cellular process. Understanding the structural basis of protein‐protein interactions can lead to the development of new drugs for treatment of various diseases.
Matteo Floris, MORO, STEFANO
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Photosynthesis Research, 2006
A computer model comprising light reactions, electron-proton transport, enzymatic reactions, and regulatory functions of C3 photosynthesis has been developed as a system of differential budget equations for intermediate compounds. The emphasis is on electron transport through PSII and PSI and on the modeling of Chl fluorescence and 810 nm absorptance ...
Agu, Laisk +2 more
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A computer model comprising light reactions, electron-proton transport, enzymatic reactions, and regulatory functions of C3 photosynthesis has been developed as a system of differential budget equations for intermediate compounds. The emphasis is on electron transport through PSII and PSI and on the modeling of Chl fluorescence and 810 nm absorptance ...
Agu, Laisk +2 more
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In silico antitarget screening
Drug Discovery Today: Technologies, 2004The need to early predict the possible failure of a drug candidate is becoming an absolute requirement in the drug discovery process. For this reason, from the initial phases of lead development, great attention is paid to the ADMET characteristics of the compounds.
RECANATINI, MAURIZIO +2 more
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2016
Information on the specificity of cis-sequences enables the design of functional synthetic plant promoters that are responsive to specific stresses. Potential cis-sequences may be experimentally tested, however, correlation of genomic sequence with gene expression data enables an in silico expression analysis approach to bioinformatically assess the ...
Julio, Bolívar +2 more
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Information on the specificity of cis-sequences enables the design of functional synthetic plant promoters that are responsive to specific stresses. Potential cis-sequences may be experimentally tested, however, correlation of genomic sequence with gene expression data enables an in silico expression analysis approach to bioinformatically assess the ...
Julio, Bolívar +2 more
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2011
In silico PCR analysis is a useful and efficient complementary method to ensure primer specificity for an extensive range of PCR applications from gene discovery, molecular diagnosis, and pathogen detection to forensic DNA typing. In silico PCR, SNPCheck, and Primer-BLAST are commonly used web-based in silico PCR tools. Their applications are discussed
Bing, Yu, Changbin, Zhang
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In silico PCR analysis is a useful and efficient complementary method to ensure primer specificity for an extensive range of PCR applications from gene discovery, molecular diagnosis, and pathogen detection to forensic DNA typing. In silico PCR, SNPCheck, and Primer-BLAST are commonly used web-based in silico PCR tools. Their applications are discussed
Bing, Yu, Changbin, Zhang
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ACS Nano, 2014
Innovations in computational nanoscience have traditionally come in conjunction with experimental innovations, but uncertainty often surrounds the trustworthiness of in silico studies. While the accuracy of simulations has been improving every year, considerably less attention has focused on dealing with increasing complexity, which may be the source ...
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Innovations in computational nanoscience have traditionally come in conjunction with experimental innovations, but uncertainty often surrounds the trustworthiness of in silico studies. While the accuracy of simulations has been improving every year, considerably less attention has focused on dealing with increasing complexity, which may be the source ...
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In Silico Fingerprinting (ISIF): A User-Friendly In Silico AFLP Program
2012The Amplified fragment Length Polymorphism (AFLP) is one of the cost-effective and useful fingerprinting techniques to study non-model species. One crucial AFLP step in the AFLP procedure is the choice of restriction enzymes and selective bases providing good-quality AFLP profiles.
Margot, Paris, Laurence, Després
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2008
Complex diseases can involve the interaction of multiple genes and environmental factors. Discovering these genes is difficult, and in silico based strategies can significantly improve their detection. Data mining and automated tracking of new knowledge facilitate locus mapping.
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Complex diseases can involve the interaction of multiple genes and environmental factors. Discovering these genes is difficult, and in silico based strategies can significantly improve their detection. Data mining and automated tracking of new knowledge facilitate locus mapping.
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Annals of the New York Academy of Sciences, 2000
Abstract: It is toxicology's job to discover a new substance's harmful effects and suggest ways to prevent or mitigate those harmful effects. This paper offers a new possibility‐in silico toxicology‐to help address this multifaceted challenge.
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Abstract: It is toxicology's job to discover a new substance's harmful effects and suggest ways to prevent or mitigate those harmful effects. This paper offers a new possibility‐in silico toxicology‐to help address this multifaceted challenge.
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