Results 221 to 230 of about 236,648 (327)

In silico modeling of patient-specific blood rheology in type 2 diabetes mellitus. [PDF]

Biophys J, 2023
Han K, Ma S, Sun J, Xu M, Qi X, Wang S, Li L, Li X.   +7 more
europepmc   +1 more source

Characterization, real-time quantification and in silico modeling of arsenate reductase (arsC) genes in arsenic-resistant Herbaspirillum sp. GW103.

Research in Microbiology, 2015
M. Govarthanan, Sang-Myeong Lee, S. Kamala-Kannan, B. Oh   +3 more
semanticscholar   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

In Silico Modeling of Stress Distribution in the Diseased Ankle Joint. [PDF]

J Clin Med
Lorkowski J, Mrzyglod MW, Pokorski M.
europepmc   +1 more source

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

Advanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang, Ying‐ying Fu, Xiaoqiang Yang, Qiuying Qin, Xinyu Su, Jiaming Fang, Yanhua Kang, Qingwen He, Zhi Ruan, Yongchang Xu   +9 more
wiley   +1 more source

Editorial: Multiscale cancer modeling, in silico oncology and digital (virtual) twins in the cancer domain

Frontiers in Physiology
Georgios S. Stamatakos, Maria Angeles Perez, Ravi Radhakrishnan   +2 more
doaj   +1 more source

Engineering a computable epiblast for in silico modeling of developmental toxicity. [PDF]

Reprod Toxicol
Barham K, Spencer R, Baker NC, Knudsen TB.   +3 more
europepmc   +1 more source

Bacterial Tyrosinase Inhibition, Hemolytic and Thrombolytic Screening, and In Silico Modeling of Rationally Designed Tosyl Piperazine-Engrafted Dithiocarbamate Derivatives. [PDF]

Biomedicines, 2023
Zahoor AF, Hafeez F, Mansha A, Kamal S, Anjum MN, Raza Z, Khan SG, Javid J, Irfan A, Bhat MA.   +9 more
europepmc   +1 more source

A Virtual Clinical Trial of Psychedelics to Treat Patients With Disorders of Consciousness

Advanced Science, EarlyView.
Disorders of consciousness after severe brain injury are marked by reduced complexity of brain activity and limited treatment options. Using personalized whole‐brain models, this study shows that simulated lysergic acid diethylamide (LSD) and psilocybin shift patient brain dynamics closer to criticality.
Naji L.N. Alnagger, Paolo Cardone, Charlotte Martial, Yonatan Sanz Perl, Iván Mindlin, Jacobo D Sitt, Leor Roseman, Robin Carhart‐Harris, David Nutt, Pablo Mallaroni, Natasha Mason, Johannes G Ramaekers, Vincent Bonhomme, Steven Laureys, Gustavo Deco, Olivia Gosseries, Pablo Núñez, Jitka Annen   +17 more
wiley   +1 more source

In Silico Modeling and Characterization of Epstein-Barr Virus Latent Membrane Protein 1 Protein. [PDF]

ACS Omega
Salam DDA, Gunasinghe KKJ, Hwang SS, Ginjom IRH, Chee Wezen X, Rahman T.   +5 more
europepmc   +1 more source