Results 141 to 150 of about 170,795 (287)
Toward the Next Generation of In Silico Modeling of Dynamic Host-Microbiota Interactions in the Skin
JID InnovationsUnderstanding how the skin microbiota contributes to skin health and disease requires knowledge of the dynamic interactions between the skin and its resident microbes.
Jamie Lee +6 more
doaj +1 more source
The Trends and Future Prospective of In Silico Models from the Viewpoint of ADME Evaluation in Drug Discovery. [PDF]
Pharmaceutics, 2023 Komura H, Watanabe R, Mizuguchi K.
europepmc +1 more source
Traction Force Microscopy for Viscoelastic Substrates: A Semi‐Analytical Method
Advanced Science, EarlyView.A semi‐analytical viscoelastic traction force microscopy framework is introduced for quantifying time‐resolved cell tractions on flat finite‐thickness substrates. The method generalizes elastic traction force microscopy to Generalized Maxwell materials, identifies when elastic approximations remain valid and, when they do not, shows that inferred ...
Adrià Villacrosa‐Ribas +10 more
wiley +1 more source
MFPD: A Multiple Fungal Pathogen Detection Pipeline Across Diverse Habitats
Advanced Science, EarlyView.The MFPD pipeline integrates a comprehensive ITS reference database of fungal pathogens, optimized parameters, and algorithms tailored for both full‐length and subregion sequences that balance accuracy and computational efficiency; it enables high‐throughput, species‐level identification from amplicon sequencing data, supporting large‐scale ...
Yi Shen +13 more
wiley +1 more source
In silico modelling of tumour-induced angiogenesis
, 2014 Angiogenesis, the process by which new vessels form from existing ones, is a key event in the development of a large and malignant vascularised tumour. A rapid expansion in in vivo and in vitro angiogenesis research in recent years has led to increased knowledge about the processes underlying angiogenesis and to promising steps forward in the ...
openaire +2 more sources
Mechanistic modelling of allergen-induced airways disease in early life
Scientific ReportsAsthma affects approximately 300 million individuals worldwide and the onset predominantly arises in childhood. Children are exposed to multiple environmental irritants, such as viruses and allergens, that are common triggers for asthma onset, whilst ...
Hannah J. Pybus +5 more
doaj +1 more source
Investigation of ER Stress in Respiratory Diseases with in Vitro and in Silico Models
, 2022 Chronic respiratory diseases are amongst the most common causes of death worldwide. Two of these are chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF).
Reijer, Jessica
core
Advanced Science, EarlyView.Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao +7 more
wiley +1 more source
Editorial: Biotribology and Biotribocorrosion Properties of Implantable Biomaterials
Frontiers in Mechanical Engineering, 2020 Alessandro Ruggiero, Hongyu Zhang
doaj +1 more source
Evolvoid: a genetic algorithm for shaping optimal cellular constructs
Journal of Biological EngineeringBackground Accurate cellular models are critical for understanding tissue function and accelerating drug discovery. While in vitro systems like spheroids and organoids are widely used, they are costly, low-throughput, and often lack reproducibility. Here,
Piera Mancini +5 more
doaj +1 more source