Results 191 to 200 of about 114,349,436 (308)

Genetic diversity and camphor profiling of <i>Curcuma caesia</i> roxb.: identification of elite genotypes and in silico prediction of gastroprotective mechanisms. [PDF]

Front Pharmacol
Isha V, Venkatesan K, Senthil N, Rajasree V, Renuka R, Chandrakumar K, Vellaikumar S, Karthikeyan P.   +7 more
europepmc   +1 more source

In Silico Prediction and In Vitro Validation of Bacterial Interactions in the Plant Rhizosphere Using a Synthetic Bacterial Community. [PDF]

Bio Protoc
Mukherjee A, Tan BH, Swarup S.
europepmc   +1 more source

RNA Promotes Synapsin Condensates That Organize Synaptic Vesicles in Live Neurons and Enable Localized Translation in Reconstituted System

Advanced Science, EarlyView.
Condensates at synapses organize synaptic vesicles (SVs) and are crucial for efficient neurotransmitter release, yet how RNA contributes to this mesoscale architecture remains poorly understood. Here we uncover that RNA modulates synapsin–driven condensates.
Branislava Rankovic, Zachary M. Geisterfer, Akshita Chhabra, Vladimir M. Jovanovic, Ian Seim, Christian Hoffmann, Antonela Condric, Gerard Aguilar Pérez, Rinse de Boer, Lars T. Hofstede, Jingao Sun, Kiara Freitag, Katja Nowick, Marina Jendrach, Frank L. Heppner, Vladimir Despic, Michaela Müller‐McNicoll, Stephan Sigrist, Geert van den Bogaart, Sofiia Reshetniak, Amy S. Gladfelter, Dragomir Milovanovic   +21 more
wiley   +1 more source

In silico prediction, molecular docking, and dynamics analysis of steroidal alkaloids from the genus Fritillaria: implications for designing novel antiparkinsonian therapeutic strategies. [PDF]

Sci Rep
Farboodniay Jahromi MA, Hashemi S, Sadeghian S, Movahedi M, Poustforoosh A, Seradj SH, Emami L.   +6 more
europepmc   +1 more source

Neuromorphic Devices and Computing for Sensing, Memory, and Control

Advanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu, Nicholas Schaffer, Xiao Yang   +2 more
wiley   +1 more source

Anti-inflammatory and antioxidant effects of Lavandula stoechas L. on human macrophages and in silico prediction of α7 nicotinic acetylcholine receptor interaction. [PDF]

BMC Complement Med Ther
Baris E, Portakal HS, Sezan Uydas S, Oztinen N, Hamurtekin E, Kosar M, Firtina Z, Tosun M.   +7 more
europepmc   +1 more source

Computationally Evidence‐Grounded Sequence‐First Design of Peptide Binders

Advanced Science, EarlyView.
BOND‐PEP enables controllable, sequence‐first peptide binder design by grounding generation in binding evidence retrieved for each target. It uses topology‐conditioned message passing to integrate relevant peptide examples with the target protein sequence, forming a residue‐level representation that guides the generation of diverse, target‐specific ...
Wenze Ding
wiley   +1 more source

The Performance of <i>In Silico</i> Prediction Tools for Variant Curation in a Panel of Cancer Genes. [PDF]

Hum Mutat
Nelson N, Niaz A, Fairfax K, Bryan TM, Lucas S, Dickinson J.   +5 more
europepmc   +1 more source

Dual‐line Genome‐scale CRISPR Screening Enables Robust Target Gene Discovery

Advanced Science, EarlyView.
A species‐optimized CRISPR platform integrates efficient piggyBac delivery, genome‐scale sgRNA libraries, and parallel screening in two independently engineered Bactrocera dorsalis Cas9 cell lines. Cross‐line consensus analysis filters line‐specific effects, enriches candidates with reproducible in vivo phenotypes, and reveals conserved, species ...
Ziniu Li, Jiao Qiao, Qiuyuan Zhang, Peipei Liu, Chenjun Zheng, Qi Zhou, Mengqi Ji, Zhihui Zhu, Xiaoxue Li, Hongyu Zhang   +9 more
wiley   +1 more source

In Silico Prediction of Secreted Proteins in Shiga Toxin-Producing <i>Escherichia coli</i>: Identification of a Hydrolase as a Robust Genomic Marker. [PDF]

Vet Sci
Vélez MV, Juárez AE, Colello R, Del Canto F, Padola NL.   +4 more
europepmc   +1 more source