Biomaterial-Based In Situ Cancer Vaccines
Advances in Materials, 2023 Cancer immunotherapies have reshaped the paradigm for cancer treatment over the past decade. Among them, therapeutic cancer vaccines that aim to modulate antigen‐presenting cells and subsequent T cell priming processes are among the first FDA‐approved ...
Yang Bo, Hua Wang
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Engineered exosomes as an in situ DC-primed vaccine to boost antitumor immunity in breast cancer
Molecular Cancer, 2022 Background Dendritic cells (DCs) are central for the initiation and regulation of innate and adaptive immunity in the tumor microenvironment. As such, many kinds of DC-targeted vaccines have been developed to improve cancer immunotherapy in numerous ...
Lanxiang Huang +10 more
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Direct observation via in situ heated stage EBSD analysis of recrystallization of phosphorous deoxidised copper in unstrained and strained conditions [PDF]
, 2020 Recrystallization of phosphorous deoxidised copper used for strength critical applications at elevated temperatures was investigated by means of in situ heated stage EBSD analysis using a Gatan Murano heated stage mounted within a Carl Zeiss Sigma FEGSEM
Kotadia, Hiren +3 more
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Models of the in Situ Formation of Detected Extrasolar Giant Planets [PDF]
, 2021 We present numerical simulations of the formation of the planetary companions to 47 UMa, ρ CrB, and 51 Peg. They are assumed to have formed in situ according to the basic model that a core formed first by accretion of solid particles, then later it ...
P. Bodenheimer, O. Hubickyj, J. Lissauer
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ReLive: Bridging In-Situ and Ex-Situ Visual Analytics for Analyzing Mixed Reality User Studies
International Conference on Human Factors in Computing Systems, 2022 The nascent field of mixed reality is seeing an ever-increasing need for user studies and field evaluation, which are particularly challenging given device heterogeneity, diversity of use, and mobile deployment.
Sebastian Hubenschmid +6 more
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In situ click chemistry generation of cyclooxygenase-2 inhibitors
Nature Communications, 2017 Cyclooxygenase-2 isozyme is a promising anti-inflammatory drug target, and overexpression of this enzyme is also associated with several cancers and neurodegenerative diseases.
A. Bhardwaj, J. Kaur, M. Wuest, F. Wuest
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In-situ sub-structure decoupling of resiliently coupled assemblies [PDF]
, 2019 The context of this paper is the increasing need for vibro-acoustic simulation across many sectors. A procedure is derived for decoupling the components of resiliently mounted assemblies.
Meggitt, JWR, Moorhouse, AT
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In situ elucidation of the active state of Co-CeOx catalysts in the dry reforming of methane: the important role of the reducible oxide support and interactions with cobalt [PDF]
, 2018 The dry reforming of methane was systematically studied over a series (2-30 wt%) of Co (~5nm in size) loaded CeO2 catalysts, with an effort to elucidate the behavior of Co and ceria in the catalytic process using in-situ methods.
Akter, Nusnin +16 more
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Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
Journal of Cell Biology, 1992 Programmed cell death (PCD) plays a key role in developmental biology and in maintenance of the steady state in continuously renewing tissues. Currently, its existence is inferred mainly from gel electrophoresis of a pooled DNA extract as PCD was shown ...
Yael Gavrieli +2 more
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Meitan xuebao, 2023 Underground in-situ pyrolysis of coal is a new trend in the utilization of coal resources in the future. It is especially critical to investigate the coal pore-fissure structure, its spatial distribution and connectivity under different pyrolysis methods,
Jianhang SHI +4 more
doaj +1 more source