Results 41 to 50 of about 918,764 (265)

Effect of long reaction distance on gas composition from organic-rich shale pyrolysis under high-temperature steam environment

open access: yesInternational Journal of Coal Science & Technology
When high-temperature steam is used as a medium to pyrolyze organic-rich shale, water steam not only acts as heat transfer but also participates in the chemical reaction of organic matter pyrolysis, thus affecting the generation law and release ...
Lei Wang   +6 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Design of a Verification Device of Motor Axle Wheel Load Scales Based on Pump-Controlled Hydraulic Cylinder

open access: yesSensors
Vehicle axle load scales are one of the most important devices for vehicle safety testing. To ensure the stability and reliability of test results, regular calibration of axle load scales is necessary.
Long Hao   +3 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Orthogonal optimization of the ratio of nano-silica sol-EVA-fly ash cement-based composite slurry and the effect on its physical properties

open access: yesMeitan xuebao
To address the problem that traditional cement-based slurry materials cannot meet the actual demand for grouting and reinforcement of large deformation roadways in coal mines, some high-performance composite slurry materials are obtained by modifying ...
Yuxu SHEN   +8 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Mechanism of mechanical strength degradation and microstructure evolution of anthracite induced by supercritical carbon dioxide

open access: yesMeitan kexue jishu
In order to reveal the effect of supercritical carbon dioxide on the mechanical strength and microstructure of anthracite in the process of CO2 injection into deep coal seams, takes anthracite as the research object, the degradation characteristics of ...
Yichao JIA   +4 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Rescue Path Planning and Simulation Analysis of Mining Robot Based on Improved A* Algorithm

open access: yesTaiyuan Ligong Daxue xuebao
Purposes The situation of post-disaster site of coal mine underground is complex. Aiming at the fact that traditional A* algorithm-based coal mine robot rescue path planning bears path insecurity, low efficiency, and other problems, and by combining with
Biying DUAN   +7 more
doaj   +1 more source

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