Results 71 to 80 of about 1,236,235 (304)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

In situ observation of bainitic transformation behavior in medium carbon bainitic steel

Journal of Materials Research and Technology, 2022
The bainitic transformation behavior of samples with different scales was observed with dilatometer (DIL), high-temperature laser scanning confocal microscope (LCSM), and environmental transmission electron microscope (ETEM).
Xiaojie Zhao, Zhinan Yang, Chunlei Zheng, Fucheng Zhang, Xiaoyan Long   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

In Situ Growth of (−201) Fiber‐Textured β‐Ga2O3 Semiconductor Tape for Flexible Thin‐Film Transistor

Advanced Electronic Materials
High‐temperature in situ growth of Ga2O3 thin film on flexible substrates for flexible/portable electronic devices is never realized because the conventional polymer substrates cannot meet the thermal‐stability requirements.
Xiao Tang, Yue Zhao, Kuang‐Hui Li, Chen Liu, Hendrik Faber, Wedyan Babatain, Che‐Hao Liao, Saravanan Yuvaraja, Vishal Khandelwal, Dhanu Chettri, Haicheng Cao, Yi Lu, Chuanju Wang, Thomas D. Anthopoulos, Xixiang Zhang, Xiaohang Li   +15 more
doaj   +1 more source

In situ stable crack growth at the micron scale [PDF]

Nature Communications, 2017
AbstractGrain boundaries typically dominate fracture toughness, strength and slow crack growth in ceramics. To improve these properties through mechanistically informed grain boundary engineering, precise measurement of the mechanical properties of individual boundaries is essential, although it is rarely achieved due to the complexity of the task ...
Giorgio Sernicola, Tommaso Giovannini, Punit Patel, James R. Kermode, Daniel S. Balint, T. Ben Britton, Finn Giuliani   +6 more
openaire   +6 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Continuous Preparation of Carbon Nanotubes/Carbon Fiber Reinforcement Using Fe-Ni Bimetallic Catalyst

Surfaces
Surface modification of carbon fibers (CFs) is a critical step in preparing carbon fiber-reinforced composites. This study developed a continuous experimental process that integrates electrochemical anodic oxidation and chemical vapor deposition to ...
Yanying Zhu, Yanxiang Wang, Jianwei Zhang, Jinghe Guo, Yingfan Li, Siao Xin, Ziyi Xu, Yanru Yuan, Dong Zhang   +8 more
doaj   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

InN and GaN/InN monolayers grown on ZnO {0001}

, 2018
Thin InN and GaN/InN films were grown on oxygen-polar (O) (000-1) and zinc-polar (Zn) (0001) zinc oxide (ZnO) by plasma-assisted molecular beam epitaxy (PAMBE).
Calarco, Raffaella, Chèze, Caroline, Ernst, Torsten   +2 more
core   +1 more source

Sb-surfactant-mediated growth of Si/Si1–yCy superlattices by molecular-beam epitaxy [PDF]

, 1995
Si/Si0.97C0.03 superlattices were grown on Si(001) substrates by molecular beam epitaxy (MBE) to study the use of Sb as a surfactant during Si1–yCy growth.
Ahn, C. C., Croke, E. T., Hunter, A. T., McGill, T. C., Pettersson, P. O.   +4 more
core   +1 more source