Results 11 to 20 of about 112,460 (347)
Liver Transplantation, 2022 Abstract In situ normothermic regional perfusion (NRP) and ex situ normothermic machine perfusion (NMP) aim to improve the outcomes of liver transplantation (LT) using controlled donation after circulatory death (cDCD). NRP and NMP have not yet been compared directly. In this international observational study, outcomes of LT performed between
Mohkam, Kayvan +29 more
openaire +5 more sources
<i>Ex vivo</i>, <i>in situ</i> perfusion protocol for human brain fixation compatible with microscopy, MRI techniques, and anatomical studies. [PDF]
Front Neuroanat, 2023 We present a method for human brain fixation based on simultaneous perfusion of 4% paraformaldehyde through carotids after a flush with saline. The left carotid cannula is used to perfuse the body with 10% formalin, to allow further use of the body for ...
Insausti R +20 more
europepmc +2 more sources
Frontiers in Immunology, 2022 Access to liver transplantation is limited by a significant organ shortage. The recent introduction of machine perfusion technology allows surgeons to monitor and assess ex situ liver function prior to transplantation. However, many donated organs are of
Siavash Raigani +17 more
doaj +2 more sources
A systematic review and meta-analysis of cold in situ perfusion and preservation of the hepatic allograft: Working toward a unified approach. [PDF]
Liver Transpl, 2017 The efficacy of cold in situ perfusion and static storage of the liver is a possible determinant of transplantation outcomes. The aim of this study was to determine whether there is evidence to substantiate a preference for a particular perfusion route ...
Hameed AM +4 more
europepmc +2 more sources
Observations on the ex situ perfusion of livers for transplantation. [PDF]
Am J Transplant, 2018 Normothermic ex situ liver perfusion might allow viability assessment of livers before transplantation. Perfusion characteristics were studied in 47 liver perfusions, of which 22 resulted in transplants.
Watson CJE +11 more
europepmc +2 more sources
Ex situ Perfusion of Pancreas for Whole-Organ Transplantation: Is it Safe and Feasible? A Systematic Review. [PDF]
J Diabetes Sci Technol, 2020 Introduction: Pancreas transplantation is currently one of the best treatments proposed in highly selected patients with unstable and brittle type 1 diabetes.
Prudhomme T +6 more
europepmc +2 more sources
Cubic Microcontainers Improve In Situ Colonic Mucoadhesion and Absorption of Amoxicillin in Rats
Pharmaceutics, 2020 An increased interest in colonic drug delivery has led to a higher focus on the design of delivery devices targeting this part of the gastrointestinal tract. Microcontainers have previously facilitated an increase in oral bioavailability of drugs.
Juliane Fjelrad Christfort +7 more
doaj +1 more source
Pharmaceutics, 2023 Chrysin is a flavonoid with various biological activities. However, its low water solubility and strong metabolism render its oral bioavailability rather poor.
Chenhui Wang +8 more
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Machine Perfusion of the Human Heart
Transplantology, 2022 This brief communication about machine perfusion of potential human donor hearts describes its historical development. Included in the review are both the isolated perfusion of donor hearts retrieved from heart beating and non-heart-beating donors ...
Stephen Large, Simon Messer
doaj +1 more source
Estimation of Catha edulis (Vahl) Forssk. ex Endl. – antidiabetic drug interactions by using closed-loop Doluisio’s method [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2023 Context: Catha edulis (khat) is a prevalent plant in Yemen and other African regions. In Yemen and other countries, most people chew this plant, which may change the pharmacokinetics of many drugs, such as anti-diabetics (glibenclamide and metformin).
Ahmed M. Al-Ghani +2 more
doaj +1 more source