Results 1 to 10 of about 1,338,212 (267)

Late toxicity after peposertib-enhanced chemoradiation in rectal cancer patients managed with organ preservation [PDF]

Clinical and Translational Radiation Oncology
Background and purpose: Combining peposertib, a DNA-PK inhibitor, with capecitabine-based chemoradiation may improve tumor response and organ preservation in rectal cancer.
W. Zambare, R. Ravella, C. Li, C.H. Crane, J.J. Cuaron, I.H. Wei, A. Wu, D. Rao, G.M. Nash, E. Pappou, V.M. Williams, M. Reyngold, P.B. Paty, M. Zinovoy, D. Roth O’Brien, L.B. Saltz, A. Cercek, M.R. Weiser, J. Garcia-Aguilar, R. Yaeger, J.J. Smith, P.B. Romesser   +21 more
doaj   +2 more sources

Organ preservation: current limitations and optimization approaches [PDF]

Frontiers in Medicine
Despite the annual rise in patients with end-stage diseases necessitating organ transplantation, the scarcity of high-quality grafts constrains the further development of transplantation.
Qiulin Ran, Jiayi Zhang, Jisheng Zhong, Ji Lin, Shuai Zhang, Guang Li, Bin You   +6 more
doaj   +2 more sources

Establishment of Functional Liver Spheroids From Human Hepatocyte-Derived Liver Progenitor-Like Cells for Cell Therapy

Frontiers in Bioengineering and Biotechnology, 2021
Globally, about two million people die from liver diseases every year. Liver transplantation is the only reliable therapy for severe end-stage liver disease, however, the shortage of organ donors is a huge limitation.
Wen-Ming Liu, Wen-Ming Liu, Xu Zhou, Xu Zhou, Cai-Yang Chen, Cai-Yang Chen, Dong-Dong Lv, Wei-Jian Huang, Wei-Jian Huang, Yuan Peng, Hong-Ping Wu, Yi Chen, Yi Chen, Dan Tang, Dan Tang, Li-Na Guo, Xiu-Li Wang, Hong-Dan Zhang, Xiao-Hua Liu, Xiao-Hua Liu, Li-Qun Yang, Li-Qun Yang, Wei-Feng Yu, Wei-Feng Yu, He-Xin Yan, He-Xin Yan, He-Xin Yan, He-Xin Yan   +27 more
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Isochoric Supercooling Organ Preservation System

Bioengineering, 2023
This technical paper introduces a novel organ preservation system based on isochoric (constant volume) supercooling. The system is designed to enhance the stability of the metastable supercooling state, offering potential long-term preservation of large ...
Gabriel Năstase, Florin Botea, George-Andrei Beșchea, Ștefan-Ioan Câmpean, Alexandru Barcu, Ion Neacșu, Vlad Herlea, Irinel Popescu, Tammy T. Chang, Boris Rubinsky, Alexandru Șerban   +10 more
doaj   +1 more source

Organ Repair and Regeneration During Ex Situ Dynamic Preservation: The Future is Nano

Transplant International, 2023
Organ preservation and assessment with machine perfusion (MP) has provided transplant physicians with the ability to evaluate and select grafts suitable for transplantation.
Nicholas Gilbo, Nicholas Gilbo, Joris Blondeel, Joris Blondeel, Jacques Pirenne, Jacques Pirenne, Renato Romagnoli, Renato Romagnoli, Giovanni Camussi, Giovanni Camussi, Diethard Monbaliu, Diethard Monbaliu   +11 more
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Editorial: Organ preservation for rectal cancer patients [PDF]

Frontiers in Surgery
Ionut Negoi, John R. T. Monson, Leonardo Bustamante-Lopez, Leonardo Bustamante-Lopez, Zoe Garoufalia, Vito D'Andrea, Sameh Hany Emile   +6 more
doaj   +2 more sources

Recent Advances in Organ Preservation Solutions and Methods for Using in Liver and Kidney Transplantation

مجله دانشکده پزشکی اصفهان, 2020
Background: The organ transplantation has been developed due to recent advances in transplantation surgery. The method of preservation and the type of preserving solution are determining factors in the outcome of the transplantations.
Zahra Jamadi, Parinaz Parhizgar, Ghasem Yazdanpanah, Tahereh Tayebi, Roghayeh Tarasi, Hassan Niknejad   +5 more
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Benign and malignant renal cells are differentially inhibited during prolonged organ preservation. [PDF]

PLoS ONE, 2013
The worry of potential residual renal cancer cells in donor kidney after resection of small renal cancer impedes the extensive use of such controversial donor source.
Nengwang Yu, Shuai Fu, Yubao Liu, Zhihou Fu, Jianzhong Meng, Zhonghua Xu, Baocheng Wang, Aimin Zhang   +7 more
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Induction chemotherapy‐based organ‐preservation protocol improve the function preservation compared with immediate total laryngectomy for locally advanced hypopharyngeal cancer—Results of a matched‐pair analysis

Cancer Medicine, 2023
Background We performed a paired analysis to compare the therapeutic effect between the induction chemotherapy‐based organ‐preservation approach and immediate total laryngectomy in hypopharyngeal squamous cell carcinoma patients requiring total ...
Yifan Yang, Ling Feng, Qi Zhong, Yang Zhang, Zhigang Huang, Shurong Zhang, Shuling Li, Junmao Gao, Lizhen Hou, Hongzhi Ma, Shizhi He, Qian Shi, Meng Lian, Yanming Zhao, Xixi Shen, Jiaming Chen, Lingwa Wang, Haiyang Li, Shaoshi Chen, Jiaqi Xu, Ru Wang, Jugao Fang   +21 more
doaj   +1 more source

Organ preservation strategy: new therapeutic alternative in rectal cancer

Journal of the Egyptian National Cancer Institute, 2023
Background The therapeutic modalities for nonmetastatic rectal cancer are presently undergoing major changes. The standard treatment is multidisciplinary, combining radiotherapy, chemotherapy, and surgery.
F. Safini, B. Amaoui, S. Semghouli, N. Aqodad   +3 more
doaj   +1 more source