Results 31 to 40 of about 297,037 (304)

Pushing the boundaries of innovation: the potential of ex vivo organ perfusion from an interdisciplinary point of view

Frontiers in Cardiovascular Medicine, 2023
Ex vivo machine perfusion (EVMP) is an emerging technique for preserving explanted solid organs with primary application in allogeneic organ transplantation.
Jasper Iske, Jasper Iske, Andreas Schroeter, Andreas Schroeter, Samuel Knoedler, Samuel Knoedler, Timo Z. Nazari-Shafti, Timo Z. Nazari-Shafti, Leonard Wert, Leonard Wert, Maximilian J. Roesel, Maximilian J. Roesel, Maximilian J. Roesel, Felix Hennig, Felix Hennig, Adelheid Niehaus, Christian Kuehn, Christian Kuehn, Christian Kuehn, Fabio Ius, Fabio Ius, Volkmar Falk, Volkmar Falk, Volkmar Falk, Volkmar Falk, Moritz Schmelzle, Arjang Ruhparwar, Arjang Ruhparwar, Arjang Ruhparwar, Axel Haverich, Axel Haverich, Axel Haverich, Christoph Knosalla, Christoph Knosalla, Christoph Knosalla, Stefan G. Tullius, Florian W. R. Vondran, Bettina Wiegmann, Bettina Wiegmann, Bettina Wiegmann   +39 more
doaj   +1 more source

Hemoglobin-Based Oxygen Carriers: Potential Applications in Solid Organ Preservation

Frontiers in Pharmacology, 2021
Ameliorating graft injury induced by ischemia and hypoxia, expanding the donor pool, and improving graft quality and recipient prognosis are still goals pursued by the transplant community.
Min Cao, Guoqing Wang, Hongli He, Ruiming Yue, Yong Zhao, Lingai Pan, Weiwei Huang, Yang Guo, Tao Yin, Lina Ma, Dingding Zhang, Xiaobo Huang   +11 more
doaj   +1 more source

Role of perfusion machines in the setting of clinical liver transplantation. A qualitative systematic review [PDF]

, 2018
Growing enthusiasm around machine perfusion (MP) in clinical liver transplantation (LT) may be the preamble for standardized practice to expand the donors' pool.
Lai, Quirino, Melandro, Fabio, Mennini, Gianluca, Pugliese, Francesco, Rossi, Massimo, Ruberto, Franco   +5 more
core   +1 more source

Organ preservation strategies: Review of literature and their applicability in developing nations

South Asian Journal of Cancer, 2014
There has been a change in practice in locally advanced laryngopharyngeal cancers toward non-surgical treatment modalities. Although, there have been landmark trials pertinent to organ preservation, their applicability in developing nations is a topic of
Mitali Dandekar, Anil D′Cruz
doaj   +1 more source

Can adenine nucleotides predict primary nonfunction of the human liver homograft? [PDF]

, 1994
Sixty-eight primary liver grafts were analyzed to see whether adenine nucleotides (AN: ATP, ADP, and AMP) or purine catabolites (PC: adenosine, inosine, hypoxanthine, and xanthine) of tissue or effluent can predict primary graft nonfunction.
Bronsther, O, Fujita, S, Hamamoto, I, Irish, W, Nakamura, K, Starzl, TE, Takaya, S, Todo, S, Van Gulik, TM   +8 more
core   +1 more source

Trends in organ preservation [PDF]

Transplant International, 2003
Organ preservation aims to provide a viable graft with primary function post-transplant. The current basis of preservation for transplantation is static cold storage using specific preservation solutions which minimise cellular swelling and membrane pump activity, thus maintaining cellular ATP levels. The current organ shortage and consequent expansion
McLaren, A, Friend, P
openaire   +2 more sources

Revolutionizing deceased donor transplantation: How new approaches to machine perfusion broadens the horizon for organ donation

Transplantation Reports
Solid organ transplantation is lifesaving for persons with end-stage organ disease. Thanks to advancements in organ preservation, surgeons are now able to successfully transplant organs that were previously considered high risk for poor graft function ...
Stephanie Almeida, William Snyder, Mita Shah, Jonathan Fisher, Christopher Marsh, Alana Hawkes, Diana Gorial, Sean DeWolf, Dianne B. McKay   +8 more
doaj   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Current practice and novel approaches in organ preservation

Frontiers in Transplantation, 2023
Organ transplantation remains the only treatment option for patients with end-stage organ failure. The last decade has seen a flurry of activity in improving organ preservation technologies, which promise to increase utilization in a dramatic fashion ...
Ozge Sila Ozgur, Ozge Sila Ozgur, Bat-Erdene Namsrai, Timothy L. Pruett, John C. Bischof, Mehmet Toner, Mehmet Toner, Erik B. Finger, Korkut Uygun, Korkut Uygun   +9 more
doaj   +1 more source

Cryopreservation of a whole liver [PDF]

, 2007
Preservation of vascularized organs such as the liver is limited to 24hrs. before destructive processes disqualify it for transplantation. This narrow time window prevents surgeons from performing optimal pathogen screening and matching tests which often
Amir Arav, Menahem Ben-Haim, Zohar Gavish   +2 more
core   +1 more source