Results 1 to 10 of about 3,949,061 (289)

New solutions in organ preservation

Transplantation Reviews, 2002
Over the last 20 years, a number of methods and solutions have been developed to preserve donor organs for transplantation. Collins et al first introduced the simple cold-storage technique to store and transport kidneys up to 30 hours. The development of the University of Wisconsin cold-storage solution (UW-CSS) in 1986 improved organ preservation and ...
'THart, N, Leuvenink, H, Ploeg, R
openaire   +3 more sources

Evaluation of the efficacy of HEMO2life®, a marine OXYgen carrier for Organ Preservation (OxyOp2) in renal transplantation: study protocol for a multicenter randomized trial

Trials, 2023
Background Preventing ischemia‒reperfusion injury (IRI) is a major issue in kidney transplantation, particularly for transplant recipients receiving a kidney from extended criteria donors (ECD). The main consequence of IRI is delayed graft function (DGF).
Yannick Le Meur, Emmanuel Nowak, Benoit Barrou, Antoine Thierry, Lionel Badet, Matthias Buchler, Jean-Philippe Rerolle, Leonard Golbin, Agnès Duveau, Jacques Dantal, Pierre Merville, Nassim Kamar, Leïla Demini, Franck Zal   +13 more
doaj   +1 more source

Evaluation of the presence of microorganisms in solid-organ preservation solution

Brazilian Journal of Infectious Diseases
OBJECTIVE: To assess the presence of microorganism contamination in the preservation solution for transplant organs (kidney/pancreas). Method: Between August 2007 and March 2008, 136 samples of preservation solution were studied prior to graft ...
André Marcelo Colvara Mattana, Alexandre Rodrigues Marra, Antônia Maria de Oliveira Machado, Gaspar de Jesus Lopes Filho, Alcides Augusto Salzedas Netto, Adriano Miziara Gonzalez   +5 more
doaj   +1 more source

A prospective, randomized, single-blind, multicentre, phase III study on organ preservation with Custodiol-N solution compared with Custodiol® solution in organ transplantation (kidney, liver and pancreas)

Trials, 2020
Background Organ preservation before transplantation is still a challenge. Both the University of Wisconsin and Bretschneider’s histidine-tryptophan-ketoglutarate (HTK; Custodiol®) solution are standard for liver, kidney and pancreas preservation.
Daniela Kniepeiss, Philipp Houben, Philipp Stiegler, Andrea Berghold, Regina Riedl, Judith Kahn, Peter Schemmer   +6 more
doaj   +1 more source

Cold Saline Perfusion before Ischemia-Reperfusion Is Harmful to the Kidney and Is Associated with the Loss of Ezrin, a Cytoskeletal Protein, in Rats

Biomedicines, 2021
Background: Organ protection for transplantation is perfusion with ice-cold preservation solutions, although saline is also used in animal experiments and living donor transplantations.
Csaba Révész, Anita A. Wasik, Mária Godó, Pál Tod, Sanna Lehtonen, Gábor Szénási, Péter Hamar   +6 more
doaj   +1 more source

The impact of topically applied preservation solutions on the respiratory epithelium of tracheal grafts submitted to cold ischemia: functional and morphological analysis

Clinics, 2013
OBJECTIVE: Advances in graft reepithelialization and revascularization have renewed interest in airway transplantation. This study aims to determine whether topically applied preservation solutions can ameliorate ischemic injury to tracheal grafts.
Artur Eugênio de Azevedo-Pereira, Juliana Akemi Saka, Karina Andrighetti de Oliveira-Braga, Rogério Pazetti, Mauro Canzian, Paulo Manuel Pêgo-Fernandes, Fabio Biscegli Jatene   +6 more
doaj  

Nanotechnology-driven advancements in organ transplantation: Multifaceted strategies for organ preservation, ischemia reperfusion injury, immunomodulation and post-transplant monitoring

Materials Today Bio
Organ transplantation faces critical challenges, including donor shortages, suboptimal preservation, ischemia-reperfusion injury (IRI), and immune rejection.
Ziyin Chen, Mingxiao Zhang, Congrong Shen, Xinyu Zhao, Jianfeng Wang, Xianwen Wang   +5 more
doaj   +1 more source

Comparative efficacy of Belzer or Euro-Collins solutions for pancreatic preservation during cold ischemic storage in rats [PDF]

Acta Cirúrgica Brasileira, 2014
PURPOSE: To compare the efficacy of different types of solutions (Belzer or Euro-Collins) for the preservation of rat pancreas during cold ischemia.METHODS: Thirty Wistar rats were divided into three groups according to the perfusion or storage solution:
Rogério Renato Perez, Alberto Goldenberg, Alcides Augusto Salzedas Netto, Adriano Miziara Gonzalez   +3 more
doaj   +2 more sources

Organ preservation solutions

Ejhp practice, 2009
Systematic research has led to continuing improvements in the solutions and techniques of preserving donated hearts. The persistent shortage of donors means that organs of lower quality are increasingly being accepted and we are turning more and more to machine perfusion of donated hearts.
Leuvenink, H, Ploeg, R
openaire   +2 more sources

Contamination of the Preservation Solution in Solid Organ Transplantation

Transplantation Proceedings, 2019
Preservation solutions (PS), in which grafts for patients undergoing liver transplantation are stored, represent a medium suitable for microorganism growth and a potential source for transmission of pathogenic germs to the transplant recipients. The aim of the present study was to review the relevant literature for the incidence and predictors of ...
Sotiropoulos, G.C., Kostakis, I.D., Prodromidou, A., Garoufalia, Z., Stamopoulos, P., Machairas, N.   +5 more
openaire   +3 more sources