Results 11 to 20 of about 3,949,061 (289)
Hyperbranched polyglycerol as a colloid in cold organ preservation solutions. [PDF]
PLoS ONE, 2015 Hydroxyethyl starch (HES) is a common colloid in organ preservation solutions, such as in University of Wisconsin (UW) solution, for preventing graft interstitial edema and cell swelling during cold preservation of donor organs.
Sihai Gao +6 more
doaj +3 more sources
Original and generic preservation solutions in organ transplantation. A new paradigm? [PDF]
Acta Cirúrgica Brasileira, 2020 Solid organ transplantation is a very complex process, in which the storage of the graft in a preservation solution is mandatory in order to extend ischemic times and contain further damage.
Joan Roselló-Catafau +5 more
doaj +3 more sources
Preservation Solutions for Kidney Transplantation: History, Advances and Mechanisms
Cell Transplantation, 2019 Solid organ transplantation was one of the greatest medical advances during the past few decades. Organ preservation solutions have been applied to diminish ischemic/hypoxic injury during cold storage and improve graft survival.
Yimeng Chen +5 more
doaj +2 more sources
A Potential Route to Reduce Ischemia/Reperfusion Injury in Organ Preservation
Cells, 2022 The pathophysiological process of ischemia and reperfusion injury (IRI), an inevitable step in organ transplantation, causes important biochemical and structural changes that can result in serious organ damage. IRI is relevant for early graft dysfunction
Marc Micó-Carnero +5 more
doaj +3 more sources
Current Opinion in Organ Transplantation, 2018 To provide an understanding of the scientific principles, which underpinned the development of organ preservation solutions, and to bring into context new strategies and challenges for solution development against the background of changing preservation technologies and expanded criteria donor access.Improvements in organ preservation solutions ...
Barry Fuller +2 more
exaly +4 more sources
Development of Supercooling Preservation Method for Adherently Cultured Endothelial Cells and Its Application to Microphysiological Systems [PDF]
CellsMicrophysiological systems (MPS) that recapitulate human organ functions have gained attention as alternatives to animal experiments in drug discovery, regenerative medicine, and toxicity assessments. However, preserving MPS with adherent cells remains a
Maaya Hikichi +2 more
doaj +2 more sources
Cadaver embalming and fixing solutions from past to present [PDF]
Ķazaķstannyṇ Klinikalyķ Medicinasy, 2022 Cadaver and organ embalming-fixing solutions have a long history. The aim of this study is to follow this historical adventure step by step and to consider the point of embalming and fixation solutions.
Seyma Toy, Yusuf Secgin
doaj +1 more source
Novel vs clinical organ preservation solutions: improved cardiac mitochondrial protection. [PDF]
J Cardiothorac Surg, 2017 Background: Heart transplantation remains the gold standard for end-stage heart failure, with current ex vivo organ storage times limited to 4 to 6 h before critical tissue damage occurs.
Ferng AS +5 more
europepmc +2 more sources
Bioengineering, 2022 Introduction: On the United States’ Organ Transplantation Waitlist, approximately 17 people die each day waiting for an organ. The situation continues to deteriorate as the discrepancy between harvested organs and the number of patients in need is ...
Jose M. Gonzalez +10 more
doaj +1 more source
Proteomic Analysis of Kidney Preservation Solutions Prior to Renal Transplantation. [PDF]
PLoS ONE, 2016 One of the main issues in kidney transplantation is the optimal functional preservation of the organ until its transplantation into the appropriate recipient. Despite intensive efforts, the functional preservation period remains limited to hours.
Abdurrahman Coskun +12 more
doaj +1 more source