Results 11 to 20 of about 1,338,212 (267)
Perspectives in Organ Preservation
Maintaining organ viability after donation until transplantation is critically important for optimal graft function and survival. To date, static cold storage is the most widely used form of preservation in every day clinical practice. Although simple and effective, it is questionable whether this method is able to prevent deterioration of organ ...
Maathuis, M, Leuvenink, H, Ploeg, R
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Trends in organ preservation [PDF]
Organ preservation aims to provide a viable graft with primary function post-transplant. The current basis of preservation for transplantation is static cold storage using specific preservation solutions which minimise cellular swelling and membrane pump activity, thus maintaining cellular ATP levels. The current organ shortage and consequent expansion
McLaren, A, Friend, P
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Organ reperfusion and preservation
Organ transplantation is one of the medical success stories of the 20th century. Transplantation is, however, a victim of its own success with demand for organs far exceeding supply. The ischemia/reperfusion injury associated with organ transplantation is complex with interlinking cellular pathways and cascades.
Jamieson, R, Friend, P
openaire +4 more sources
Improvement of lung preservation - From experiment to clinical practice [PDF]
Background. Reperfusion injury represents a severe early complication following lung transplantation. Among the pathogenetic factors, the high potassium content of Euro-Collins(R) solution is discussed.
Hatz, Rudolf A. +7 more
core +1 more source
Clinical assessment of Renal Ischaemic Injury and the Role of Cryopreservation; Peritoneal Cooling an Non-Heart-Beating Donation and Topical Cooling for Laparoscopic Surgery [PDF]
The project aims focussed on three main areas of study; ischaemic injury assessment, laparoscopic renal cryopreservation and peritoneal cooling for non-heart-beating organ donation.
Navarro, Alex
core +6 more sources
Transplanting Marginal Organs in the Era of Modern Machine Perfusion and Advanced Organ Monitoring
Organ transplantation is undergoing profound changes. Contraindications for donation have been revised in order to better meet the organ demand. The use of lower-quality organs and organs with greater preoperative damage, including those from donation ...
Thomas Resch +9 more
doaj +1 more source
Comprehensive review of the application of MP and the potential for graft modification
IntroductionFollowing procurement, the liver graft is exposed to an ischemic period that triggers several pathophysiologic changes in response to oxygen deprivation.
Paola A. Vargas +2 more
doaj +1 more source
ET-Kyoto solution (ET-K) is an extracellular-type organ preservation solution containing the cytoprotective disaccharide, trehalose. A previous study reported the supplement of dibutyryl cyclic adenosine monophosphate (db-cAMP) in conventional ET-K to ...
Xiangdong Zhao +7 more
doaj +1 more source
Incidence of individual organ dysfunction in fatal acute pancreatitis: analysis of 1024 death records [PDF]
Background: Extrapancreatic organ dysfunction is the key determinant of mortality in acute pancreatitis (AP). This study aimed to document the frequency and duration of individual organ dysfunction in all fatalities caused by AP in a large, population ...
Parks, Rowan W.; id_orcid +15 more
core +1 more source
Persufflation—Current State of Play
With the ever-increasing disparity between the number of patients waiting for organ transplants and the number organs available, some patients are unable to receive life-saving transplantation in time.
Aaron John Buhagiar +2 more
doaj +1 more source

