Results 11 to 20 of about 97,814 (298)

Trends in organ preservation [PDF]

Transplant International, 2003
Organ preservation aims to provide a viable graft with primary function post-transplant. The current basis of preservation for transplantation is static cold storage using specific preservation solutions which minimise cellular swelling and membrane pump activity, thus maintaining cellular ATP levels. The current organ shortage and consequent expansion
McLaren, A, Friend, P
openaire   +3 more sources

Perspectives in Organ Preservation

Transplantation, 2007
Maintaining organ viability after donation until transplantation is critically important for optimal graft function and survival. To date, static cold storage is the most widely used form of preservation in every day clinical practice. Although simple and effective, it is questionable whether this method is able to prevent deterioration of organ ...
Maathuis, M, Leuvenink, H, Ploeg, R
openaire   +4 more sources

Organ reperfusion and preservation

Frontiers in Bioscience, 2008
Organ transplantation is one of the medical success stories of the 20th century. Transplantation is, however, a victim of its own success with demand for organs far exceeding supply. The ischemia/reperfusion injury associated with organ transplantation is complex with interlinking cellular pathways and cascades.
Jamieson, R, Friend, P
openaire   +4 more sources

Experimental organ preservation

Journal of British Surgery, 1972
Abstract An experimental model for the study of organ preservation based on the isolated, biologically perfused rat heart is described. Using this model a standard storage solution has been evolved for use with initial perfusion and hypothermic storage. This solution contains Dextran 40 and insulin.
K C, Calman, P R, Bell
openaire   +4 more sources

Organ preservation: which temperature for which organ? [PDF]

Journal of International Medical Research, 2019
In 1954, Joseph Murray performed the first successful human organ transplant from a live kidney donor, Richard Herrick, into the donor’s twin, Robert. Since no form of organ preservation was available, the surgeries happen in two simultaneous operating ...
Maria Irene Bellini, Vito D’Andrea
doaj   +2 more sources

Induction chemotherapy‐based organ‐preservation protocol improve the function preservation compared with immediate total laryngectomy for locally advanced hypopharyngeal cancer—Results of a matched‐pair analysis

Cancer Medicine, 2023
Background We performed a paired analysis to compare the therapeutic effect between the induction chemotherapy‐based organ‐preservation approach and immediate total laryngectomy in hypopharyngeal squamous cell carcinoma patients requiring total ...
Yifan Yang, Ling Feng, Qi Zhong, Yang Zhang, Zhigang Huang, Shurong Zhang, Shuling Li, Junmao Gao, Lizhen Hou, Hongzhi Ma, Shizhi He, Qian Shi, Meng Lian, Yanming Zhao, Xixi Shen, Jiaming Chen, Lingwa Wang, Haiyang Li, Shaoshi Chen, Jiaqi Xu, Ru Wang, Jugao Fang   +21 more
doaj   +1 more source

Organ preservation strategy: new therapeutic alternative in rectal cancer

Journal of the Egyptian National Cancer Institute, 2023
Background The therapeutic modalities for nonmetastatic rectal cancer are presently undergoing major changes. The standard treatment is multidisciplinary, combining radiotherapy, chemotherapy, and surgery.
F. Safini, B. Amaoui, S. Semghouli, N. Aqodad   +3 more
doaj   +1 more source

Improvement of lung preservation - From experiment to clinical practice [PDF]

, 2002
Background. Reperfusion injury represents a severe early complication following lung transplantation. Among the pathogenetic factors, the high potassium content of Euro-Collins(R) solution is discussed.
Hatz, Rudolf A., Schelling, G., Bittmann, I., Schildberg, Friedrich Wilhelm, Müller, Ch., Reichart, B., Kellner, B., Fürst, H.   +7 more
core   +1 more source

Transplanting Marginal Organs in the Era of Modern Machine Perfusion and Advanced Organ Monitoring

Frontiers in Immunology, 2020
Organ transplantation is undergoing profound changes. Contraindications for donation have been revised in order to better meet the organ demand. The use of lower-quality organs and organs with greater preoperative damage, including those from donation ...
Thomas Resch, Benno Cardini, Rupert Oberhuber, Annemarie Weissenbacher, Julia Dumfarth, Christoph Krapf, Claudia Boesmueller, Dietmar Oefner, Michael Grimm, Sefan Schneeberger   +9 more
doaj   +1 more source

Incidence of individual organ dysfunction in fatal acute pancreatitis: analysis of 1024 death records [PDF]

, 2009
Background: Extrapancreatic organ dysfunction is the key determinant of mortality in acute pancreatitis (AP). This study aimed to document the frequency and duration of individual organ dysfunction in all fatalities caused by AP in a large, population ...
Parks, Rowan W.; id_orcid, Bayanne Olabi, Garden, O. James, Parks, Rowan W., O. James Garden, Mole, DJ, Robinson, Victoria, Damian J. Mole, Olabi, Bayanne, Victoria Robinson, Mole, Damian J., Parks, RW, Garden, OJ, Olabi, B, Robinson, V, Rowan W. Parks   +15 more
core   +1 more source