Results 231 to 240 of about 112,460 (347)

Adipose‐derived small extracellular vesicles exacerbate microvascular dysfunction in heart failure with preserved ejection fraction via mmu‐miR‐582‐3p‐mediated Rap1b suppression

Interdisciplinary Medicine, EarlyView.
This study reveals that small extracellular vesicles (sEVs) from visceral fat compromise coronary microcirculation in a mouse model of heart failure with preserved ejection fraction (HFpEF). The SGLT2 inhibitor canagliflozin emerges as a therapeutic strategy, improving cardiac function and endothelial health.
Lu Chen, Qiuhan Wang, Mengjia Shen, Mingjue Li, Yingqi Zhu, Cankun Zheng, Siyuan Ma, Hairuo Lin, Xiaokang Fu, Rui Zhang, Jianping Bin, Yulin Liao, Qiancheng Wang   +12 more
wiley   +1 more source

Normothermic regional perfusion for donation after circulatory death in lung transplantation. [PDF]

Front Cardiovasc Med
Gorton AJ, Mohammadi DK, Malik MJ, Keshavamurthy S.   +3 more
europepmc   +1 more source

A Simplified Risk Assessment Tool to Predict Post Deceased Donor Liver Transplantation Outcomes: A Single, Highly Experienced Medical Center in Taiwan

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Liver transplantation (LT) is the standard treatment for end‐stage liver disease, yet the gap between the demand for organs and their availability is widening. In Taiwan, the scarcity of deceased donor organs highlights the need for optimized utilization strategies.
Jie‐Lan Jhang, Hao‐Chien Hung, Yin Lai, Jin‐Chiao Lee, Yu‐Chao Wang, Chih‐Hsien Cheng, Tsung‐Han Wu, Chen‐Fang Lee, Ting‐Jung Wu, Hong‐Shiue Chou, Kun‐Ming Chan, Wei‐Chen Lee   +11 more
wiley   +1 more source

Managing the meniscus part I—Anatomy, biomechanics, and treatment strategies for the atraumatic meniscus tear

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The purpose of this article is to serve as the first of a two‐part review on the meniscus; in this review, we will establish the background on anatomy and pathogenesis of the meniscus, as well as the effect of the meniscus on native knee kinematics and function.
Ehab M. Nazzal, Jonathan D. Hughes, Armin Runer, Matthew P. Kolevar, Jorge Chahla, Robert G. Marx, James J. Irrgang, Roman Seil, Berte Bøe, David Parker, Ryosuke Kuroda, Eric H. Senorski, Sachin Tapasvi, Volker Musahl   +13 more
wiley   +1 more source

Impact of ischemia duration on MRI-derived perfusion parameters in a mouse kidney transplant model. [PDF]

Eur Radiol Exp
Herr FL, Kloiber-Langhorst S, Li MM, Dietrich O, Erdelkamp R, Walz C, Jacobi S, Wirth U, Ricke J, Cyran CC, Andrassy J.   +10 more
europepmc   +1 more source

Convergence of Organ‐on‐a‐Chip and Freeform Printing of Sacrificial Poly(2‐cyclopropyl‐2‐oxazoline) Enables the Generation of Perfusable Endothelialized Channels in Hydrogels

Macromolecular Rapid Communications, EarlyView.
We employ freeform printing of thermo‐responsive poly(2‐oxazoline) to directly fabricate suspended sacrificial vascular templates within Organ‐on‐a‐chip devices. This enables circular, perfusable channels down to 200 µm without post‐processing.
Giulia Maria Di Gravina, Patrick Kuntschke, Zeno Guttenberg, Philipp Linke, Katja P. Schumann, Meike N. Leiske, Thomas Scheibel, Matthias Ryma   +7 more
wiley   +1 more source

Scientific and Technical Considerations of the World's First Beating Heart Transplantation in a Human: An Operator's View. [PDF]

JACC Case Rep
Huang S, Zhou Z, Feng K, Chen J, Xiong M, Liang M, Wu Z.   +6 more
europepmc   +1 more source

Nano Delivery Strategy Opens Effective Avenues for the Treatment of Colorectal Cancer

Medicine Bulletin, EarlyView.
ABSTRACT Colorectal cancer (CRC) presents significant therapeutic challenges because of chemoresistance, systemic toxicity, and the complexity of the tumor microenvironment (TME). Nanodrug delivery systems (NDDS) have emerged as versatile platforms capable of overcoming these limitations by enhancing tumor accumulation, improving pharmacokinetics, and ...
Qiurong Wei, Yunli Xu, Tianjiao Zhang, Shuyu Xu, Haonan Wang, Yuan Wang, Xinxin Xie, Xiaolong Liang   +7 more
wiley   +1 more source

Ex-Situ Dual Hypothermic Oxygenated Machine Perfusion in Full-Left-Full-Right Split Liver Transplantation for Two Adult Recipients. [PDF]

J Clin Med
Kobryń K, Frankowska A, Rykowski P, Bartkowiak M, Zhylko A, Morawski M, Stypułkowski J, Masior Ł, Smoter P, Patkowski W, Grąt M.   +10 more
europepmc   +1 more source

A morphometric analysis of isolated Torpedo electric organ synaptic vesicles following stimulation. [PDF]

, 1990
Dowe, G., Fox, G., Koetting, D.
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