Results 241 to 250 of about 112,460 (347)

Preoperative VEGFR‐TKI Plus ICI Therapy Facilitates 3D‐Guided Cytoreductive Nephron‐Sparing Surgical Feasibility and Immune Remodeling in Advanced Renal Cell Carcinoma

open access: yesMed Research, EarlyView.
Preoperative VEGFR‐TKI plus ICI therapy in advanced ccRCC normalizes tumor vasculature, enhances CD8⁺ T/B cell infiltration, and promotes TLS maturation, leading to profound tumor microenvironment remodeling. These immunologic changes improve the feasibility of 3D reconstruction‐guided robotic cytoreductive nephron‐sparing surgery, resulting in reduced
Wenhao Xu   +10 more
wiley   +1 more source

In situ fenestration of a frozen elephant trunk prosthesis to recanalize the left subclavian artery. [PDF]

open access: yesJ Vasc Surg Cases Innov Tech
Apostolidis G   +5 more
europepmc   +1 more source

Breakdown of C3 complement and IgG in peritonitis exudate-pathophysiological aspects and therapeutic approach [PDF]

open access: yes, 1988
Billing, A.   +5 more
core  

Cerebral in situ ischemic postconditioning: From bench to bedside and beyond

open access: yesNeuroprotection, EarlyView.
This review explores the translational potential of in situ ischemic postconditioning in acute ischemic stroke. Preclinical and clinical evidence is summarized to highlight its promise as a neuroprotective strategy in the era of endovascular therapy.
Xiao Jiang   +4 more
wiley   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto   +2 more
wiley   +1 more source

Hydrogel Microneedle Array‐Based Transdermal Dressing System for Multiplexed Assessment and Intelligent Therapy of Chronic Wounds

open access: yesSmall, EarlyView.
This work develops a theranostic wound microneedle dressing integrates a therapeutic MXene‐infused hydrogel with a high‐conductive sensor array enabled by a novel laser‐scribing technique. The platform actively promotes wound healing and provides antibacterial action while continuously monitoring seven key biomarkers.
Md Sharifuzzaman   +6 more
wiley   +1 more source

Spatiotemporal Co‐Delivery of Hydrogen and Magnesium via Microneedle Patches for Neuroinflammation Modulation After Spinal Cord Injury: A Multi‐Modal In Vivo Study

open access: yesSmall, EarlyView.
A spatiotemporal co‐delivery microneedle system (MN‐Mg) is developed for spinal cord injury repair. By generating hydrogen gas and magnesium ions in situ, this dual‐engine platform effectively scavenges ROS and modulates microglial polarization via the MAPK/AP‐1 signaling axis.
Haibo Wang   +13 more
wiley   +1 more source

Human intestinal and multivisceral transplantation [PDF]

open access: yes, 1994
Abu-Elmagd, K   +8 more
core  

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