Results 271 to 280 of about 112,460 (347)

Bile formation in long-term ex situ perfused livers

Surgery, 2021
Long-term ex situ liver perfusion may rescue injured grafts. Little is known about bile flow during long-term perfusion. We report the development of a bile stimulation protocol and motivate bile flow as a viability marker during long-term ex situ liver perfusion.Porcine and human livers were perfused with blood at close to physiologic conditions.
Eshmuminov, Dilmurodjon, Schuler, Martin J, Becker, Dustin, Bautista Borrego, Lucia, Mueller, Matteo, Hagedorn, Catherine, Häusler, Stephanie, Steiger, Julia, Tibbitt, Mark W, Dutkowski, Philipp, Rudolf von Rohr, Philipp, Stieger, Bruno, Hefti, Max, Clavien, Pierre-Alain   +13 more
openaire   +3 more sources

Intestinal Absorption by Perfusion in Situ

Journal of Applied Physiology, 1957
An apparatus and technique for the perfusion of a specific cannulated segment of small intestine of the rat, in situ, have been described. By the removal and analysis of perfusate samples from the system, continuous intestinal absorption curves have been established from a single animal in the steady state.
F A, JACOBS, M, LUPER
openaire   +2 more sources

Hypothermic Ex Situ Perfusion of Human Limbs With Acellular Solution for 24 Hours

Transplantation, 2020
Supplemental Digital Content is available in the text. Background. Machine perfusion (MP) has evolved as a promising approach for the ex situ preservation in organ transplantation.
V. Haug, B. Kollár, S. Tasigiorgos, Y. Endo, Martin Kauke, Ali-Farid Safi, Anamika Veeramani, Obada Abdulrazzak, B. Bausk, David R. Walt, B. Pomahac   +10 more
semanticscholar   +1 more source

IN SITU CADAVER KIDNEY PERFUSION

Transplantation, 1981
Lactated Ringers and Collins C2 solutions were compared in different volumes for rapid intra-aortic in situ cooling of pig cadaver kidneys. Both solutions in large volumes caused renal damage when compared with ex vivo flushed controls, although C2 was less injurious.
R T, Schweizer, B A, Sutphin, S A, Bartus   +2 more
openaire   +2 more sources

Improved in situ rat liver perfusion technique

Journal of Surgical Research, 1980
Abstract A compact, in situ rat liver perfusion system was designed for accurate and precise control of liver temperature at preselected ambient temperatures from 31 to 45 ± 0.1°C. The system employed a thermostatically controlled perfusion cabinet and water jacketed perfusate reservoirs.
F G, Collins, J L, Skibba
openaire   +2 more sources

Defatting of Human Livers During Long-Term ex situ Normothermic Perfusion: Novel Strategy to Rescue Discarded Organs for Transplantation

Annals of Surgery, 2023
Objective: To develop a protocol for the defatting of steatotic liver grafts during long-term ex situ normothermic machine perfusion. Background: Despite the alarming increase in donor organ shortage, the highly prevalent fatty liver grafts are often ...
R. X. Sousa Da Silva, Lucia Bautista Borrego, Daniela Lenggenhager, F. Huwyler, Jonas Binz, L. Mancina, E. Breuer, K. Wernlé, M. Hefti, M. Müller, Leslie Cunningham, M. D. de Oliveira, H. Petrowsky, Achim Weber, P. Dutkowski, W. Hoffmann, Anurag Gupta, M. Tibbitt, B. Humar, P. Clavien   +19 more
semanticscholar   +1 more source

Randomized study on in situ liver perfusion techniques: Gravity perfusion VS high-pressure perfusion

Transplantation Proceedings, 1997
T HE VIABILITY of the donor liver depends on many factors such as perfusion techniques, perfusion solution and preservation methods. To date a number of studies have focused on perfusion solutions and preservation methods, but little is known about the effects of perfusion techniques and flow rate on organ viability in the clinical setting. In situ the
TISONE, GIUSEPPE, Vennarecci, G, BAIOCCHI, LEONARDO, Negrini, S, Palmieri, GP, ANGELICO, MARIO, Dauri, M, Casciani, CU   +7 more
openaire   +3 more sources

The Current Landscape of Liver Transplantation After Ex Situ Machine Perfusion and Normothermic Regional Perfusion in the United States

Liver transplantation, 2022
In the United States, there remains a discrepancy between the number of liver transplantation (LT) candidates awaiting transplantation and the availability of donor organs.
K. Croome, Shennen A. Mao, C. Taner
semanticscholar   +1 more source

Liver transplantation of partial grafts after ex situ splitting during hypothermic oxygenated perfusion—The HOPE–Split pilot study

Liver transplantation, 2022
Partial liver grafts from ex situ splitting are considered marginal due to prolonged static cold storage. The use of ex situ hypothermic oxygenated perfusion (HOPE) may offer a strategy to improve preservation of ex situ split grafts.
G. Rossignol, X. Muller, V. Hervieu, S. Collardeau-Frachon, Antoine Breton, Natacha Boulanger, M. Lesurtel, R. Dubois, K. Mohkam, J. Mabrut   +9 more
semanticscholar   +1 more source

Perfusion of the Isolated Adrenals in Situ

American Journal of Physiology-Legacy Content, 1958
A technique is described in which the circulation of the adrenal glands of the dog is completely isolated on the arterial side as well as on the venous side. With this technique the adrenal glands can be perfused in situ and, if desired, in vivo without any interruption of their blood supply and without any direct trauma.
J G, HILTON, D C, WEAVER, G, MUELHEIMS, V V, GLAVIANO, R, WEGRIA   +4 more
openaire   +2 more sources