Results 51 to 60 of about 112,460 (347)

Normothermic Ex Situ Heart Perfusion With the Organ Care System for Cardiac Transplantation: A Meta-analysis

open access: yesTransplantation, 2022
Background. Heart transplantation (HTx) is, at present, the most effective therapy for end-stage heart failure patients; however, the number of patients on the waiting list is rising globally, further increasing the gap between demand and supply of ...
S. J. Langmuur   +5 more
semanticscholar   +1 more source

Machine Perfusion of the Liver: A Review of Clinical Trials

open access: yesFrontiers in Surgery, 2021
Although efforts have been made by transplant centers to increase the pool of available livers by extending the criteria of liver acceptance, this practice creates risks for recipients that include primary non-function of the graft, early allograft ...
Nikolaos Serifis   +5 more
doaj   +1 more source

A Vascular Microphysiological Model of Lung Fibrosis Reveals That Myofibroblasts and IPF Patient‐Derived Fibroblasts Impair Angiogenesis and Vasculogenesis

open access: yesAdvanced Functional Materials, EarlyView.
A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria   +7 more
wiley   +1 more source

Extended left hepatectomy for intrahepatic cholangiocarcinoma: hepatic vein reconstruction with in-situ hypothermic perfusion and extracorporeal membrane oxygenation

open access: yesBMC Surgery, 2018
Background Liver resection for intrahepatic cholangiocarcinoma (ICC) with invasion of the inferior vena cava (IVC) and hepatic veins (HV) is a challenging procedure. Case presentation We report a case of a 63-year-old woman with a 6-cm, centrally located
Deniz Balci   +9 more
doaj   +1 more source

Proteomic analysis of perfusate from in situ rat placenta perfusion

open access: yesjournal of Proteome Science and Computational Biology, 2014
Abstract Background: The placenta is the most important organ for the development of the embryo and fetus because of its transport functions.
Lilong Wei   +5 more
openaire   +1 more source

An in vivo biosensor for neurotransmitter release and in situ receptor activity. [PDF]

open access: yes, 2010
Tools from molecular biology, combined with in vivo optical imaging techniques, provide new mechanisms for noninvasively observing brain processes. Current approaches primarily probe cell-based variables, such as cytosolic calcium or membrane potential ...
Griesbeck, Oliver   +6 more
core   +2 more sources

Dynamic Metabolic Changes During Prolonged Ex Situ Heart Perfusion Are Associated With Myocardial Functional Decline

open access: yesFrontiers in Immunology, 2022
Ex situ heart perfusion (ESHP) was developed to preserve and evaluate donated hearts in a perfused beating state. However, myocardial function declines during ESHP, which limits the duration of perfusion and the potential to expand the donor pool.
M. Olkowicz   +12 more
semanticscholar   +1 more source

Shape‐Morphing Nanoengineered Hydrogel Ribbons as Hemostats

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces a self‐assembling, shape‐morphing nanoengineered hydrogel ribbon system that rapidly forms porous aggregates in situ for efficient hemostasis in trauma and surgical applications. Abstract Rapid and effective hemorrhage control remains a major challenge in trauma and surgical care, particularly for complex or noncompressible wounds.
Ryan Davis Jr   +9 more
wiley   +1 more source

Normothermic ex situ pancreas perfusion for the preservation of porcine pancreas grafts

open access: yesAmerican Journal of Transplantation, 2022
Pancreas transplantation improves and extends the life of patients with insulin‐dependent diabetes. Pancreata from extended criteria donors have been increasingly used due to the scarcity of available grafts.
L. Mazilescu   +8 more
semanticscholar   +1 more source

MAGTWIST: A Magnetically‐Driven Rotary Actuator Using a Traveling‐Wave With Integrated Stiffness Tunability

open access: yesAdvanced Functional Materials, EarlyView.
MAGTWIST: A compact magnetic rotary actuator, enabling smooth, stepless rotation, and on‐demand locking. Inspired by peristalsis, a soft polymer belt generates a traveling‐wave, enabling 270° rotation when heated. Cooling stiffens the belt, locking it in position and enabling it to withstand high loads.
Simon Frieler   +3 more
wiley   +1 more source

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