Results 71 to 80 of about 112,460 (347)

A Cardioprotective perfusion protocol limits myocardial functional decline during ex situ heart perfusion

JHLT Open
Background: Ex situ heart perfusion is associated with a significant decline in graft quality related to oxidative stress, inflammation, endothelial dysfunction, and metabolic perturbations.
Mats T. Vervoorn, MD, Elisa M. Ballan, MSc, Sjoerd van Tuijl, MSc, Saskia C.A. de Jager, PhD, Selma E. Kaffka genaamd Dengler, MD, Joost P.G. Sluijter, PhD, Pieter A. Doevendans, MD, PhD, Niels P. van der Kaaij, MD, PhD   +7 more
doaj   +1 more source

Mimickers of chronic thromboembolic pulmonary hypertension on imaging tests: a review

Pulmonary Circulation, 2020
Chronic thromboembolic pulmonary hypertension (CTEPH) is caused by mechanical obstruction of large pulmonary arteries secondary to one or more episodes of pulmonary embolism.
Shraddha Narechania, Rahul Renapurkar, Gustavo A. Heresi   +2 more
doaj   +1 more source

Treatment of large renal allograft arterial pseudoaneurysm with in situ cold perfusion, ex vivo vascular reconstruction and reimplantation [PDF]

Journal of Nephropathology, 2019
Background: Pseudoaneurysm after renal transplantation is a rare but serious complication. Case Presentation: We report a case of a 76-year-old man who presented six weeks after kidney transplant with a large pseudoaneurysm arising from the renal artery ...
Brent Taiting Xia, Aleksandr Aleksandrovich Reznichenko, Madison Colyn Cuffy, Ervin Steve Woodle   +3 more
doaj   +1 more source

The Absorption Characteristics of Nonvolatile Components in a Water Extraction From Amomi fructus as Determined by In Situ Single-Pass Intestinal Perfusion and High-Performance Liquid Chromatography

Frontiers in Pharmacology, 2020
Background Amomi fructus is a famous traditional Chinese medicine (TCM) that can exert beneficial effects during the treatment of gastrointestinal diseases and is used widely in China and other countries in Southeast Asia. However, the nonvolatile active
Yuebao Yao, Wenjuan Mi, Guang-zhao Cao, Ruiqi Yang, Huirong Chen, Yong Liu, Hui-qin Zou, Yonghong Yan   +7 more
semanticscholar   +1 more source

Smart Catheters for Diagnosis, Monitoring, and Therapy

Advanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman, Samiha Ahmed, Majed Othman Althumayri, Megan Guy, Darlenne Chavez Lugo, Frances S. Ligler, George T. Ligler, Rahmi Oklu, Hiroshi Kawahira, Michael J. McShane, Jun Kameoka, Jonathan Bova, Hatice Ceylan Koydemir   +12 more
wiley   +1 more source

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

Advanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu, Wentie Yang, Youzhi Hong, Yusen Qiao, Chaozhao Liang   +4 more
wiley   +1 more source

Normothermic Perfusion is Superior to Cold Perfusion in Porcine Ex Situ Lung Perfusion

Transplantation Proceedings
Cold ex situ lung perfusion (ESLP) has demonstrated improved preservation in small animal ESLP compared to normothermic ESLP and cold static preservation. We hypothesized that cold negative pressure ventilation (NPV)-ESLP would improve graft function in a porcine transplantation model.Four perfusate temperatures were examined with 12 hours NPV-ESLP in ...
Keir Forgie, Nicholas Fialka, Abeline Watkins, Katie Du, Sayed Himmat, Sanaz Hatami, Mubashir Khan, Xiuhua Wang, Ryan Edgar, Katie-Marie Buswell-Zuk, Darren H. Freed, Jayan Nagendran   +11 more
openaire   +2 more sources

Ex situ heart perfusion: A novel platform to test cardiovascular therapeutics in human hearts

JHLT Open
Background: Explanted hearts from recipients undergoing cardiac transplantation may be utilized as a human model of cardiomyopathy. Ex-situ perfusion of hearts allows control of the physiological and biochemical conditions of perfusion.
John Onsy Louca, Magnus Althage, Marco Öchsner, Aravinda Page, Joao Pedro Nunes, Catherine Wilson, Sanjay Sinha, Simon Messer, James Matt Bae, Mostin Hu, Nicole Asemota, Sarah Fielding, Sai Bhagra, Neil Henderson, Johnny Lindquist, Daniela Später, Anna Collén, Kaushik Sengupta, Benjamin Challis, Justin Perkins, Stephen Large   +20 more
doaj   +1 more source

Oxygen and ROS Delivery for Infected Wound Healing and Future Prospects

Advanced Healthcare Materials, EarlyView.
Bacterial infection is a major driver of delayed wound healing and postsurgical readmissions; with rising antibiotic resistance, solid peroxide–releasing biomaterials offer sustained delivery of ROS/O2 for antimicrobial control and microenvironmental modulation.
Ayden Watt, Chably Rachella, Charlotte Jaloux, Joshua Vorstenbosch, Adam Hart, Michael Tanzer, Geraldine Merle, Jake Barralet   +7 more
wiley   +1 more source

Controlled Delivery of Sdf-1 Alpha and Igf-1: Cxcr4(+) Cell Recruitment and Functional Skeletal Muscle Recovery [PDF]

, 2015
Therapeutic delivery of regeneration-promoting biological factors directly to the site of injury has demonstrated its efficacy in various injury models.
Farrar, Roger P., Hammers, David W., Hsieh, Pei-Ling, Merscham-Banda, Melissa, Pham, Chantal B., Rybalko, Viktoriya Y., Suggs, Laura J.   +6 more
core   +1 more source