Results 21 to 30 of about 22,288 (256)

Development of a New Lunar Regolith Simulant using an Automated Program Framework

Journal of Astronomy and Space Sciences
Nowadays, the trend in lunar exploration missions is shifting from prospecting lunar surface to utilizing in-situ resources and establishing sustainable bridgehead.
GyeongRok Kwon, Kyeong Ja Kim, Eungseok Yi   +2 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Combustion Synthesis Technology for a Sustainable Settlement Overnight

Eurasian Chemico-Technological Journal, 2018
Space technology has been developed for frontier exploration not only in low-earth orbit environment but also beyond the earth orbit to the Moon and Mars, where material resources might be strongly restricted and almost impossible to be resupplied from
O. Odawara
doaj   +1 more source

Towards a Biomanufactory on Mars

Frontiers in Astronomy and Space Sciences, 2021
A crewed mission to and from Mars may include an exciting array of enabling biotechnologies that leverage inherent mass, power, and volume advantages over traditional abiotic approaches.
Aaron J. Berliner, Aaron J. Berliner, Jacob M. Hilzinger, Jacob M. Hilzinger, Anthony J. Abel, Anthony J. Abel, Matthew J. McNulty, Matthew J. McNulty, George Makrygiorgos, George Makrygiorgos, Nils J. H. Averesch, Nils J. H. Averesch, Soumyajit Sen Gupta, Soumyajit Sen Gupta, Alexander Benvenuti, Alexander Benvenuti, Daniel F. Caddell, Daniel F. Caddell, Stefano Cestellos-Blanco, Stefano Cestellos-Blanco, Anna Doloman, Anna Doloman, Skyler Friedline, Skyler Friedline, Davian Ho, Davian Ho, Wenyu Gu, Wenyu Gu, Avery Hill, Avery Hill, Paul Kusuma, Paul Kusuma, Isaac Lipsky, Isaac Lipsky, Mia Mirkovic, Mia Mirkovic, Jorge Luis Meraz, Jorge Luis Meraz, Vincent Pane, Vincent Pane, Kyle B. Sander, Kyle B. Sander, Fengzhe Shi, Fengzhe Shi, Jeffrey M. Skerker, Jeffrey M. Skerker, Alexander Styer, Alexander Styer, Kyle Valgardson, Kyle Valgardson, Kelly Wetmore, Kelly Wetmore, Sung-Geun Woo, Sung-Geun Woo, Yongao Xiong, Yongao Xiong, Kevin Yates, Kevin Yates, Cindy Zhang, Cindy Zhang, Shuyang Zhen, Shuyang Zhen, Bruce Bugbee, Bruce Bugbee, Douglas S. Clark, Douglas S. Clark, Douglas S. Clark, Devin Coleman-Derr, Devin Coleman-Derr, Ali Mesbah, Ali Mesbah, Somen Nandi, Somen Nandi, Somen Nandi, Robert M. Waymouth, Robert M. Waymouth, Peidong Yang, Peidong Yang, Peidong Yang, Peidong Yang, Craig S. Criddle, Craig S. Criddle, Karen A. McDonald, Karen A. McDonald, Karen A. McDonald, Lance C. Seefeldt, Lance C. Seefeldt, Amor A. Menezes, Amor A. Menezes, Adam P. Arkin, Adam P. Arkin, Adam P. Arkin   +91 more
doaj   +1 more source

Mars In Situ Resource Utilization Technology Evaluation [PDF]

50th AIAA Aerospace Sciences Meeting including the New Horizons Forum and Aerospace Exposition, 2012
We have examined the technologies required to enable Mars In-Situ Resource Utilization (ISRU) because our understanding of Mars resources has changed significantly in the last five years as a result of recent robotic missions to the red planet. Two major developments, (1) confirmation of the presence of near-surface water in the form of ice in very ...
Anthony Muscatello, Edgardo Santiago-Maldonado   +1 more
openaire   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

From Earth to Mars: a perspective on exploiting biomineralization for Martian construction

Frontiers in Microbiology
The future of Mars colonization hinges on the ability to construct durable infrastructure using locally available resources. Given the high cost and logistical complexity of transporting construction materials to Mars, the development of autonomous in ...
Shiva Khoshtinat, Jared Long-Fox, Seyed Mohammad Javad Hosseini   +2 more
doaj   +1 more source

Plasmas for in situ resource utilization on Mars: Fuels, life support, and agriculture

Journal of Applied Physics, 2022
This work discusses the potential of combining non-thermal plasmas and conducting membranes for in situ resource utilization (ISRU) on Mars. By converting different molecules directly from the Martian atmosphere, plasmas can create the necessary feed-stock and base chemicals for processing fuels, breathing oxygen, building materials, and fertilizers ...
Guerra, V., Silva, T., Pinhão, N., Guaitella, O., Guerra-Garcia, C., Peeters, F., Tsampas, M., van de Sanden, M.   +7 more
openaire   +3 more sources