Results 71 to 80 of about 777,304 (305)
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Following the Mw 5.5 earthquake of 9 November 2022 that occurred along the Adriatic coast of Italy and the related seismic sequence, we analysed new data from deep wells drilled in recent years by ENI S.p.A.
Paola Montone, Maria Teresa Mariucci
doaj +1 more source
Use of borehole imaging to improve understanding of the in-situ stress orientation of Central and Northern England and its implications for unconventional hydrocarbon resources. [PDF]
New interest in the potential for shale gas in the United Kingdom (UK) has led to renewed exploration for hydrocarbons in the Carboniferous age Bowland–Hodder shales under Central and Northern England.
Fellgett, Mark W. +2 more
core +1 more source
ABSTRACT Objectives WHO grade 4 astrocytomas are associated with poor prognosis, and their prognostic factors remain controversial. This study aimed to identify the prognostic factors and develop a management algorithm for these patients. Methods This study retrospectively included 151 CNS5 adult grade 4 astrocytomas from two medical centers.
Jiawei Cai +13 more
wiley +1 more source
Natural fractures are important storage spaces and seepage channels in tight carbonate reservoirs. It is therefore of practical significance to quantitatively predicting their development and distribution patterns and revealing the dominant geological ...
XU Ke
doaj +1 more source
During the multistage fracturing of shale gas horizontal wells, casing damage frequently occurs, making it essential to evaluate casing stress and deformation.
Yu Su +8 more
doaj +1 more source
Understanding the deformation mechanism of individual phases of a ZrTi-based bulk metallic glass matrix composite using in situ diffraction and imaging methods [PDF]
The plasticity of a ZrTi-based bulk metallic glass composite consisting of glassy matrix and crystalline dendritic phase was studied in-situ under identical tensile loading conditions using scanning electron microscopy and synchrotron X-ray diffraction ...
Connolley, Thomas +3 more
core +2 more sources
Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source
Crystalline to amorphous phase transformation during initial lithiation in (100) silicon-wafers is studied in an electrochemical cell with lithium metal as the counter and reference electrode.
A. McCormick +6 more
core +1 more source
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt +8 more
wiley +1 more source

