Results 161 to 170 of about 7,982,325 (356)

MIF as an oncogenic driver of low‐heterogeneity melanomas

open access: yesMolecular Oncology, EarlyView.
Shvefel and colleagues identified tumor‐secreted macrophage migration inhibitory factor (MIF) as an upregulated cytokine that mediates immune resistance in melanomas with low‐intratumoral heterogeneity. MIF and its functional paralogue D‐dopachrome tautomerase (D‐DT or MIF‐2) have overlapping but nonidentical signaling functions and are hypothesized to
Thuy T. Tran   +4 more
wiley   +1 more source

Preparation of Viable Human Neurites for Neurobiological and Neurodegeneration Studies

open access: yesCells
Few models allow the study of neurite damage in the human central nervous system. We used here dopaminergic LUHMES neurons to establish a culture system that allows for (i) the observation of highly enriched neurites, (ii) the preparation of the neurite ...
Markus Brüll   +4 more
doaj   +1 more source

Liquid-liquid phase separation of proteins is modulated by amino acids in vitro and in vivo by regulating protein-protein interactions [PDF]

open access: yesarXiv
Liquid liquid phase separation (LLPS) of proteins is an intracellular process that is widely used by cells for many purposes. In living cells (in vivo), LLPS occurs in complex and crowded environments. Amino acids (AAs) are vital components of such environments, occupying a significant fraction of the cellular volume.
arxiv  

Effect of Some Compounds on the Tubercle Bacilli <i>in vitro</i>. V

open access: bronze, 1953
Masukazu Naito   +3 more
openalex   +2 more sources

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Studies on the Antibacterial Activity of some Organic Compounds <i>in vitro</i>. IV

open access: bronze, 1953
Fukujiro Fujikawa   +6 more
openalex   +2 more sources

Reductive modification of genetically encoded 3-nitrotyrosine sites in alpha synuclein expressed in E.coli

open access: yesRedox Biology, 2019
Tyrosine nitration is a post-translational protein modification relevant to various pathophysiological processes. Chemical nitration procedures have been used to generate and study nitrated proteins, but these methods regularly lead to modifications at ...
Hanne R. Gerding   +7 more
doaj  

Treatment of in vitro produced embryos with colonystimulating factor 2 during culture in the presence of serum does not affect pregnancy rates after embryo transfer. [PDF]

open access: yes
Edição dos resumos da 37ª Annual Meeting of the Brazilian Embryo Technology Society, 2024, Atibaia ...
ANUNCIAÇÃO, R. A. da   +7 more
core  

Effect of some Compounds on the Tubercle Bacilli <i>in vitro</i>. VI

open access: bronze, 1953
Masukazu Naito   +6 more
openalex   +2 more sources

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