MIF as an oncogenic driver of low‐heterogeneity melanomas
Shvefel and colleagues identified tumor‐secreted macrophage migration inhibitory factor (MIF) as an upregulated cytokine that mediates immune resistance in melanomas with low‐intratumoral heterogeneity. MIF and its functional paralogue D‐dopachrome tautomerase (D‐DT or MIF‐2) have overlapping but nonidentical signaling functions and are hypothesized to
Thuy T. Tran+4 more
wiley +1 more source
Preparation of Viable Human Neurites for Neurobiological and Neurodegeneration Studies
Few models allow the study of neurite damage in the human central nervous system. We used here dopaminergic LUHMES neurons to establish a culture system that allows for (i) the observation of highly enriched neurites, (ii) the preparation of the neurite ...
Markus Brüll+4 more
doaj +1 more source
Liquid-liquid phase separation of proteins is modulated by amino acids in vitro and in vivo by regulating protein-protein interactions [PDF]
Liquid liquid phase separation (LLPS) of proteins is an intracellular process that is widely used by cells for many purposes. In living cells (in vivo), LLPS occurs in complex and crowded environments. Amino acids (AAs) are vital components of such environments, occupying a significant fraction of the cellular volume.
arxiv
Effect of Some Compounds on the Tubercle Bacilli <i>in vitro</i>. V
Masukazu Naito+3 more
openalex +2 more sources
The Effect of “Tween 80” in Vitro on the Bacteriostatic Activity of Twenty Compounds for Mycobacterium tuberculosis [PDF]
Anne S. Youmans, Guy P. Youmans
openalex +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Studies on the Antibacterial Activity of some Organic Compounds <i>in vitro</i>. IV
Fukujiro Fujikawa+6 more
openalex +2 more sources
Tyrosine nitration is a post-translational protein modification relevant to various pathophysiological processes. Chemical nitration procedures have been used to generate and study nitrated proteins, but these methods regularly lead to modifications at ...
Hanne R. Gerding+7 more
doaj
Treatment of in vitro produced embryos with colonystimulating factor 2 during culture in the presence of serum does not affect pregnancy rates after embryo transfer. [PDF]
Edição dos resumos da 37ª Annual Meeting of the Brazilian Embryo Technology Society, 2024, Atibaia ...
ANUNCIAÇÃO, R. A. da+7 more
core
Effect of some Compounds on the Tubercle Bacilli <i>in vitro</i>. VI
Masukazu Naito+6 more
openalex +2 more sources