Results 171 to 180 of about 7,982,325 (356)

THE IN VITRO METABOLISM OF ESTROGENS BY THE LIVER STUDIED BY MEANS OF A COLORIMETRIC METHOD 12 [PDF]

, 1952
Seymour Lieberman, Henry J. Tagnon, Phyllis Schulman   +2 more
openalex   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Physiologically‐based pharmacokinetic modeling of prominent oral contraceptive agents and applications in drug–drug interactions

CPT: Pharmacometrics & Systems Pharmacology
Considerable interest remains across the pharmaceutical industry and regulatory landscape in capabilities to model oral contraceptives (OCs), whether combined (COCs) with ethinyl estradiol (EE) or progestin‐only pill.
Gareth J. Lewis, Deepak Ahire, Kunal S. Taskar   +2 more
doaj   +1 more source

Demonstrating the principal mechanism of action of medical devices intended for vaginal use on reconstructed human vaginal epithelium: the case of two hyaluronic acid-containing devices

Frontiers in Drug Safety and Regulation
Regulation (EU) 2017/745 on medical devices (MDR) has significantly modified the rules to be adopted for MD qualifications and classification. New requirements require robust evidence on mechanisms of action (MoAs) that cannot be produced by existing ...
Marisa Meloni, Barbara De Servi, Francesco Carriero, Emmanuelle Simon O’Brien, Dounia Houamel, Philippe Deruelle, Vincent Castagné   +6 more
doaj   +1 more source

Influencing Factors for Bacteriostatic Effect of TBI in vitro on Human Type of Tubercle Bacilli

, 1953
Takamasa Ueno
openalex   +2 more sources

MEASUREMENT OF THE GROWTH OF TISSUES IN VITRO [PDF]

, 1921
Albert H. Ebeling
openalex   +1 more source

CD44v, S1PR1, HER3, MET and cancer‐associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb

FEBS Open Bio, EarlyView.
Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano, Kouki Okita, Shogo Okazaki, Soshi Yoshimoto, Sachiko Masuko, Hideki Yagi, Kazunori Kato, Yoshihisa Tomioka, Kenichi Imai, Yoichi Hamada, Kazue Masuko, Kayoko Shimada‐Takaura, Noriaki Nagai, Hideyuki Saya, Tomio Arai, Toshiyuki Ishiwata, Takashi Masuko   +16 more
wiley   +1 more source

THE NUTRITION OF ANIMAL TISSUES CULTIVATED IN VITRO [PDF]

, 1957
Joseph F. Morgan, Helen J. Morton
openalex   +1 more source

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

FEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang, Yukun Xu, Yujia Li, Yiming Pang, Xueting Ding, Raorao Zhou, Dan Liang, Xianda Che, Yuanyu Zhang, Chunfang Wang, Wenjin Li, Pengcui Li   +11 more
wiley   +1 more source

EFFECTS OF VARIOUS IMMUNE RABBIT SERUMS ON THE CELLS OF SEVERAL TRANSPLANTED MOUSE LYMPHOMAS IN VITRO AND IN VIVO [PDF]

, 1957
Steven C. Mohos, John G. Kidd
openalex   +1 more source