Results 211 to 220 of about 3,958,292 (318)

Correction: The Role of Abutment Preparation Strategies in Optimizing the Bond Strength of Resin-Bonded Fixed Partial Dentures: An In Vitro Study. [PDF]

Cureus
Abdussalam A, Rajagopal P, Karumuthil JM.   +2 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

NAMs for closing knowledge gaps in assessment of respiratory uptake - a PARC project. [PDF]

Front Toxicol
Billat PA, Hansen T, De Bruijn V, Boufalaas R, Stefano S, Sosnowska A, Kohl Y, Verstraelen S, Camassa LMA, Spänig M, Gabriel C, Sarigiannis D, Krätschmer K, Raitano G, Bulawska N, Ratier A, Zienolddiny-Narui S, Chary A, Serchi T, Viegas S, Mollerup S, Escher SE, Staal YCM.   +22 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Effects of Xylazole on cAMP and Monoamine Neurotransmitters in Rats: In Vitro and In Vivo. [PDF]

Cells
Hou X, Ma T, Zhao Y, Wang X, Wu Y, Fan H, Zhang S.   +6 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Extracellular vesicles in bovine reproduction: their journey from gametogenesis to pregnancy. [PDF]

Front Cell Dev Biol
Cajas YN, Mazzarella R, Hamdi M, Millán de la Blanca G, da Silveira JC, Lima Verde-Leal C, González E, Rizos D, Cañón-Beltrán K.   +8 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

<i>DHQS</i> regulates pollen-pistil interaction via the shikimic acid pathway in <i>Arabidopsis thaliana</i>. [PDF]

Plant Signal Behav
Wang X, Peng X.
europepmc   +1 more source