Results 271 to 280 of about 5,663,004 (310)
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2017
???????????????? ?????????????? ???????????? ?????? ???????????????????? ?????????????????????????? ?????????????????? ???????????????? ?????????????????? in vitro ?? ?????????????????????????? ???? ???????????????????????? ?????????????????? ?????????????????????? ???????????????????? ??????????????????. ???????????????????????? ???????????????????????
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???????????????? ?????????????? ???????????? ?????? ???????????????????? ?????????????????????????? ?????????????????? ???????????????? ?????????????????? in vitro ?? ?????????????????????????? ???? ???????????????????????? ?????????????????? ?????????????????????? ???????????????????? ??????????????????. ???????????????????????? ???????????????????????
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Drug Safety, 1990
The development of in vitro models is advancing rapidly, with the application of cell culture methods as an alternative to animals in toxicological screening; non-cellular systems are also being used. Any screening test, whether for detecting irritants, carcinogens or teratogens should be well validated against known animal studies.
openaire +2 more sources
The development of in vitro models is advancing rapidly, with the application of cell culture methods as an alternative to animals in toxicological screening; non-cellular systems are also being used. Any screening test, whether for detecting irritants, carcinogens or teratogens should be well validated against known animal studies.
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Trends in Biochemical Sciences, 1992
Understanding the basis of specificity in an intermolecular interaction is a common if difficult task; designing a specific intermolecular interaction is much more challenging. A new technique is described that has applications to both problems, at least with regard to nucleic acids.
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Understanding the basis of specificity in an intermolecular interaction is a common if difficult task; designing a specific intermolecular interaction is much more challenging. A new technique is described that has applications to both problems, at least with regard to nucleic acids.
openaire +2 more sources
Probing the links between in vitro potency, ADMET and physicochemical parameters
Nature Reviews Drug Discovery, 2011Anne Hersey, Matthew Paul Gleeson
exaly