Results 101 to 110 of about 120,147,022 (302)

In vitro germination and viability of pollen grain of coconut accessions1

Revista Ciência Agronômica
Storage as a means of maintaining the pollen viability is important for the preservation of the genetic variability, facilitates the exchange of germplasm and greatly contributes to the generation of variability obtained from artificial crosses ...
Catrine Regina Feitosa Moura, Caroline de Araújo Machado, Ana da Silva Lédo   +2 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Effect of a short-term in vitro exposure time on the production of in vitro produced piglets

Journal of Animal Reproduction and Biotechnology, 2016
Although piglets have been delivered by embryo transfer (ET) with in vitro produced (IVP) embryos and blastocysts, a success rate has still remained lower level.
In-Sul Hwang, Dae-Jin Kwon, Tae-Uk Kwak, Joo-Young Lee, Nam-Woong Hyung, Hyeon Yang, Keon Bong Oh, Sun-A Ock, Eung-Woo Park, Gi-Sun Im, Seongsoo Hwang   +10 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

GENE-TRANSFER INTO SATELLITE CELL FROM REGENERATING MUSCLE - BUPIVACAINE ALLOWS BETA-GAL TRANSFECTION AND EXPRESSION IN-VITRO AND IN-VIVO

, 1994
In Vitro Cell Dev Biol Anim. 1994 Feb;30A(2):131-3. Gene transfer into satellite cell from regenerating muscle: bupivacaine allows beta-Gal transfection and expression in vitro and in vivo. Cantini M, Massimino ML, Catani C, Rizzuto R, Brini M, Carraro U.
BRINI, MARISA, RIZZUTO, ROSARIO, CATANI C, MASSIMINO ML, CANTINI, MARCELLO, CARRARO, UGO   +5 more
core   +1 more source

In vitro GERMINATION AND INDUCTION OF MORPHOGENETIC RESPONSES IN PITAHAYA (Hylocereus undatus (HAW.) BRITTON & ROSE)

Tropical and Subtropical Agroecosystems
Background. Hylocereus undatus is a plant of great economic importance that produces an edible fruit known as Pitahaya or dragon fruit. However, these methods result in a reduced genetic base and low germination rates, in addition to the low germination ...
Nadia Guadalupe Sánchez-Coello, Luis Carlos Ortega-Macareno, Mauricio Luna-Rodríguez, Alejandro Salinas-Castro, Dulce María Murrieta-Hernández, Daniel Lopez-Lima   +5 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Metabolism of glutathione and ascorbate in lingonberry cultivars during in vitro and ex vitro propagation

, 2013
Lingonberry (Vaccinium vitis-idaea L. ssp. vitis-idaea Britton) cultivars Regal, Splendor, and Erntedank were obtained by conventional softwood cuttings (taken as a control), by in vitro shoot proliferation of node explants, and by adventitious shoot ...
S. C. Debnath, P. Vyas, A. U. Igamberdiev   +2 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source