Results 21 to 30 of about 1,346,762 (310)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

In Vitro Initiation, Regeneration, and Characterization of Plants Derived from Mature Tetraploid Floral Explants of Date Palm (Phoenix dactylifera L.)

Horticulturae
A stable tetraploid date palm mutant with the potential for increased fruit size was recovered from a sectorial di-tetraploid chimera via the in vitro culture of flower explants.
Ahmed Othmani, Amel Sellemi, Monia Jemni, Karim Kadri, Leen Leus, Stefaan P. O. Werbrouck   +5 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

The Promising Potential of Triploidy in Date Palm (Phoenix dactylifera L.) Breeding

Plants
Date palms are a vital part of oasis ecosystems and are an important source of income in arid and semi-arid areas. Crossbreeding is limited due to the long juvenile stage of date palms and their dioecious nature.
Ahmed Othmani, Hammadi Hamza, Karim Kadri, Amel Sellemi, Leen Leus, Stefaan P. O. Werbrouck   +5 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Micropropagação do porta-enxerto de macieira 'Seleção 69' tolerante à podridão do colo (Phytophthora cactorum) Micropropagation of 'Seleção 69' apple rootstock tolerant the rotting (Phytophthora cactorum)

Ciência Rural, 2001
A utilização de porta-enxertos anões, tolerantes a problemas fitossanitários da cultura da macieira, como a podridão do colo (Phytophthora cactorum), pode aumentar o rendimento e reduzir os custos de produção.
Claudete Santa-Catarina, Scheila da Conceição Maciel, Frederico Denardi, Enio Luiz Pedrotti   +3 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

In vitro fabric culture methods to develop the initial material for triticale breeding in the Volga region

Зерновое хозяйство России, 2020
The current paper presents the estimation efficiency results of in vitro fabric culture methods used to develop the initial material for triticale breeding in the Povolzhie.
V. N. Akinina, T. I. Diyachuk, S. V. Zhilin, E. V. Kalashnikova   +3 more
doaj   +1 more source

In Vitro Porcine (Explant) Colon Culture

, 2023
Models have been extensively used to investigate disease pathogenesis. Animal models are costly and require extensive logistics for animal care, and samples are not always suitable for different analytical techniques or to answer the research question.
de Oliveira Costa, Matheus, Dame, Michael K.   +1 more
openaire   +3 more sources