Results 91 to 100 of about 14,911 (263)

The effect of the dried Gracilaria spp. undergoing different drying methods on in vitro rumen fermentation

Czech Journal of Animal Science
Seaweed has an important role in the mitigation of enteric methane (CH4) production by ruminant animals. The utilisation and its effectiveness in enteric CH4 reduction require a preservation process.
Farwa Shakeel, Yeni Widiawati, Sharly Asmairicen, Agung Purnomoadi, Agustin Herliatika, Yenny Nur Anggraeny, Setiasih Setiasih, Muhammad Rizwan, Ruslan Abdul Gopar (email: rusl005@b   +8 more
doaj   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Degradabilidad ruminal in situ e in vitro de la metionina protegida

Revista Mexicana de Ciencias Pecuarias, 2012
En dietas para rumiantes, los aminoácidos son rápidamente degradados por los microorganismos del rumen, por lo que se han protegido análogos de metionina (RPMet) a la degradación ruminal para incrementar el flujo del aminoácido al duodeno.
Alejandro Lara Bueno, Germán David Mendoza Martínez, José Ricardo Bárcena Gama, Luis León Landois Palencia, Maria Teresa Sánchez Torres, Carlos Miguel García Bojalil, José Ayala Oseguera   +6 more
doaj  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Potential use of Wolffia globosa powder supplementation on in vitro rumen fermentation characteristics, nutrient degradability, microbial population, and methane mitigation

Scientific Reports
This study examined the potential of duckweed powder (DWP) on in vitro fermentation characteristics, nutrient degradability, microbial change, and methane (CH4) production using in vitrostudy technique.
Uswatun Muslykhah, Chaichana Suriyapha, Srisan Phupaboon, Sunisa Pongsub, Maharach Matra, Gamonmas Dagaew, Sukruthai Sommai, Metha Wanapat   +7 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

A Combination of Lactic Acid Bacteria and Molasses Improves Fermentation Quality, Chemical Composition, Physicochemical Structure, in vitro Degradability and Rumen Microbiota Colonization of Rice Straw. [PDF]

Front Vet Sci, 2022
Chen X, Ma Y, Khan MZ, Xiao J, Alugongo GM, Li S, Wang Y, Cao Z.   +7 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source