Results 81 to 90 of about 14,911 (263)

FRACIONAMENTO E CINÉTICA DA FERMENTAÇÃO RUMINAL in vitro DOS CARBOIDRATOS DE CINCO VARIEDADES DE CANA-DE-AÇÚCAR

Ciência Animal Brasileira, 2010
The objective of this study was to determine the chemical composition, the carbohydrates fractionation and the kinetics of in vitro ruminal fermentation of fibrous and non-fibrous carbohydrates of five sugarcane varieties. Variety SP79-1011 presented the
Pedro Gomes da Cruz, Mauro Pereira de Figueiredo, Luiz Gustavo Ribeiro Pereira, Keityane Boone Bergamaschi, Carlindo Santos Rodrigues, Carmen Lúcia de Souza Rech   +5 more
doaj  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Influence of sugarcane bagasse on <i>in vitro</i> degradability, rumen characteristics, nutrients digestibility, blood parameters and milk production of lactating buffaloes. [PDF]

Anim Biotechnol, 2023
Abd El-Mola AA, Elnesr SS.
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Digestibility of canola seeds treated by autoclaving and/or condensed tannins

Revista Colombiana de Ciencias Pecuarias, 2014
Background: plant proteins are susceptible to rapid degradation in the rumen therefore it is important to explore the best way to improve protein utilization.
Geraldo T Dos Santos, Francilaine E De Marchi, Julio C Damasceno, Claudete R Alcalde, Antonio F Branco, Cloves C Jobim, Ulysses Cecato, Fabio S Dos Santos   +7 more
doaj  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Microbial Community, Fermentation Quality, and in vitro Degradability of Ensiling Caragana With Lactic Acid Bacteria and Rice Bran. [PDF]

Front Microbiol, 2022
You J, Zhang H, Zhu H, Xue Y, Cai Y, Zhang G.   +5 more
europepmc   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Testing thawed rumen fluid to assess in vitro degradability and its link to phytochemical and fibre contents in selected herbs and spices

Open Agriculture
This study used thawed rumen fluid (TRF) to assess in vitro degradability and its relationship with the phytochemical and fibre contents of four herbs (green tea leaves, great burnet leaves, eucalyptus leaves, and oregano leaves) and five spices (black ...
Merkhan Kawa, Standen James, Chaudhry Abdul Shakoor   +2 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source