Results 111 to 120 of about 88,172 (307)

Physicochemical Characterization of Hydroxyapatite Hybrids with Meloxicam for Dissolution Rate Improvement

Molecules
Organic–inorganic hybrids represent a good solution to improve the solubility and dissolution rates of poorly soluble drugs whose number has been increasing in the last few years. One of the most diffused inorganic matrices is hydroxyapatite (HAP), which
Lauretta Maggi, Valeria Friuli, Beatrice Cerea, Giovanna Bruni, Vittorio Berbenni, Marcella Bini   +5 more
doaj   +1 more source

Natural Bone‐Derived Ceramic Scaffolds Functionalized with Chitosan‐Gold, Chitosan‐Magnesium, and Chitosan‐Zinc for Enhanced Antibacterial Activity

Advanced Engineering Materials, EarlyView.
This study reports the development of antibacterial ceramic scaffolds derived from natural bovine bone. The bones were processed through sequential boiling and hydrogen peroxide treatment to remove organic matter, producing porous, mineral‐rich scaffolds.
Mohamad Hassan Taherian, Anh Thi Le, Anh Thi Van Le, Dung My Thi Dang, Tin Chanh Duc Doan, Chien Mau Dang, Martin Bolduc   +6 more
wiley   +1 more source

Comparative Assessment of Different Dissolution Apparatus for Floating Drug Delivery Systems

, 2006
Dissolution testing is an in vitro technique of greatimportance in formulation and development of phar-maceutical dosage forms,as it can be used as a substi-tute for in vivo studies under strictly defined and specified conditions (1).
Pramod G. Yeole, Atul D. Kar
core  

Using PBPK to Simulate Target Biopredictive Dissolution Profiles for Long‐Acting Injectables ‐ Where to Begin With Critical Bioavailability Attributes?

CPT: Pharmacometrics & Systems Pharmacology
Long‐acting injectables (LAI) are of increasing interest as they facilitate improved medication adherence and exposure, with target plasma concentration levels maintained over weeks/months.
Hannah Cleary, Nikoletta Fotaki, Tim Persoons, Deirdre M. D'Arcy   +3 more
doaj   +1 more source

Impact of Different Drying Processes on the Physico-Chemical Properties of Liquitablet Formulations Containing Lornoxicam

Pharmaceutics
Background: Enhancing bioavailability is the target of most pharmaceutical research; this can be achieved by modifying the physico-chemical characteristics of poorly water-soluble drugs intended for oral administration using different techniques.
Csilla Balla-Bartos, Alaa Gamiel, Anett Motzwickler-Németh, Rita Ambrus   +3 more
doaj   +1 more source

Deciphering nifedipine in vivo delivery from modified release dosage forms: Identification of food effect

Acta Pharmaceutica, 2015
With the increased reliance on in vitro dissolution testing as an indicator of in vivo drug behavior and the trend towards the in silico modeling of dosage form performance, the need for bioperformance dissolution methodology development has been ...
Ilić Marija, Kovačević Ivan, Parojčić Jelena   +2 more
doaj   +1 more source

Long-Acting Injectable Antipsychotics-A Review on Formulation and In Vitro Dissolution. [PDF]

Pharmaceutics, 2023
Markowicz-Piasecka M, Kubisiak M, Asendrych-Wicik K, Kołodziejczyk M, Grzelińska J, Fabijańska M, Pietrzak T.   +6 more
europepmc   +1 more source

Printed Integrated Logic Circuits Based on Chitosan‐Gated Organic Transistors for Future Edible Systems

Advanced Functional Materials, EarlyView.
Edible electronics needs integrated logic circuits for computation and control. This work presents a potentially edible printed chitosan‐gated transistor with a design optimized for integration in circuits. Its implementation in integrated logic gates and circuits operating at low voltage (0.7 V) is demonstrated, as well as the compatibility with an ...
Giulia Coco, Valerio Francesco Annese, Valerio Galli, Ilaria Penna, Debora Russo, Marina Veronesi, Rita Scarpelli, Stefania Sabella, Mario Caironi   +8 more
wiley   +1 more source

In vitro simulation of human digestion: Chemical and mechanical behavior

, 2016
The drug release pattern from an orally administrated pharmaceutical dosage form can be significantly affected by simultaneous food intake and drug administration due to the changes in the gastrointestinal physiology, in particular because of the pH ...
DALMORO, ANNALISA, CASCONE, SARA, TITOMANLIO, Giuseppe, BARBA, Anna Angela, D'AMORE, Matteo, LAMBERTI, Gaetano   +5 more
core   +1 more source

In vitro bioequivalence study of nine brands of artesunate tablets marketed in Nigeria [PDF]

Journal of Vector Borne Diseases, 2008
Background & objectives: The availability of numerous brands of artesunate in our drug market today places clinicians and pharmacists in a difficult situation of choice of a suitable brand or the possibility of alternative use.
C.O. Esimone, F.B.C. Okoye, B.U. Onah, C.S. Nworu, E.O. Omeje   +4 more
doaj