Results 251 to 260 of about 486,388 (376)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Optimized patient-derived lung cancer organoids recapitulating the immune landscape for precision therapy evaluation. [PDF]

Cell Oncol (Dordr)
Xing H, Liu R, Chen Y, Chen X, Gao X, Shen C, Zhang S, Tang Y, Wu L, You M, Xu P, Xia B.   +11 more
europepmc   +1 more source

Control of contaminants during introduction and establishment of Bambusa vulgaris in vitro

, 2016
Gustavo Rubens de Castro Torres, Laureen Michelle Houllou, Robson Antônio De Souza   +2 more
openalex   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Micropropagation and somaclonal variation in Iranian genotypes of garlic (Allium sativum L.). [PDF]

PLoS One
Afzaz MH, Mozafari J, Sanjari S.
europepmc   +1 more source

Establishment and Characterization of Eye Muscle Cell Line from Snow Trout, Schizothorax richardsonii (Gray, 1832), a Vulnerable Coldwater Fish, for In Vitro Studies

, 2020
Sanjeev Kumar, Pankaj Soni, Neha Singh, Ravindra Kumar, Shreya Srivastava, Akhilesh Kumar Mishra, Vijay Kumar Singh, Basdeo Kushwaha   +7 more
openalex   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Construction and application of pancreatic exocrine organoid and spheroid for drug screening and precision medicine. [PDF]

Front Cell Dev Biol
Tan X, Huang B, Yang X, Wang P, Hu L.
europepmc   +1 more source

Establishment of in vitro models for Neutrophil granulocytes

, 2013
submitted by Sandra Lemesch Zsfassung in dt. und engl.
openaire  

Establishment of inflammatory in vitro intestinal epithelial models for translational animal nutrition

, 2019
Tamil Selvi Sundaram, Carlotta Giromini, R. Rebucci, Ashish Baldi   +3 more
openalex   +1 more source