Results 131 to 140 of about 49,467 (343)

Demographics of infertility and management of unexplained infertility [PDF]

, 2012
Peer ...
Bhattacharya, Brandes, Brandes, Broekmans, Cantineau, Collins, Collins, Custers, Deaton, Eimers, Gleicher, Goverde, Gurunath, Guzick, Hughes, Hughes, Hull, Hunault, Hunault, Maheshwari, Mohan S. Kamath, Murdoch, National Institute for Health and Clinical Excellence, Oei, Pandian, Pashayan, Pellicer, Reindollar, Royal College of Obstetricians and Gynaecologists Infertility Guideline Group, Siladitya Bhattacharya, Siristatisdis, Snick, Soliman, Steures, te Velde, The Practice Committee of the American Society for Reproductive Medicine, The Practice Committee of the American Society for Reproductive Medicine, The Practice Committee of the American Society for Reproductive Medicine Educational Bulletin, van der Steeg, Veltman-Verhulst, Wordsworth   +40 more
core   +1 more source

Ferroptosis: The Demise of Cells Through Phospholipid Peroxidation

Advanced Science, EarlyView.
The relative abundance of peroxidation‐resistant monounsaturated fatty acids (MUFAs) vs. peroxidation‐sensitive polyunsaturated fatty acids (PUFAs) incorporated into phospholipid (PL) is a key determinant of ferroptosis sensitivity, as the peroxidation of PL PUFA acyl chains (PUFA‐PL) disrupts membrane integrity, causing ferroptotic cell death ...
Shaojie Cui, Jin Ye
wiley   +1 more source

Predicting the chances of a live birth after one or more complete cycles of in vitro fertilisation: population based study of linked cycle data from 113 873 women

British medical journal, 2016
Objective To develop a prediction model to estimate the chances of a live birth over multiple complete cycles of in vitro fertilisation (IVF) based on a couple’s specific characteristics and treatment information.
D. Mclernon, E. Steyerberg, E. T. te Velde, Amanda J Lee, S. Bhattacharya   +4 more
semanticscholar   +1 more source

The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos

Advanced Science, EarlyView.
Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan, Yelian Yan, Yalin Liang, Kanghua Zhong, Zhican Fu, Xiaobo Wang, Chao Liu, Tao Huang, Keliang Wu   +8 more
wiley   +1 more source

Machine Learning‐Driven Digital Twin of a Field‐Effect Transistor‐Based Hormone Biosensor for Real‐Time Estradiol Monitoring

Advanced Intelligent Systems, EarlyView.
A machine learning‐driven digital twin simulates an aptamer‐functionalized BioFET measuring 17β‐estradiol. Real‐time Isd signals are processed, features are extracted, and trained models estimate hormone concentration. In parallel, a one‐step‐ahead forward model learns biosensor dynamics and generates realistic synthetic signals, enabling in silico ...
Anastasiia Gorelova, Alexandra Parichenko, Shirong Huang, Santiago Melia, Gianaurelio Cuniberti   +4 more
wiley   +1 more source

MTCA‐Net: Multi‐Task Cascade Analysis Network for Real‐Time Sperm Quality Analysis

Advanced Intelligent Systems, EarlyView.
This article proposes MTCA‐Net, a multi‐task cascaded analysis network for real‐time sperm quality assessment in intracytoplasmic sperm injection. The framework integrates detection, tracking, and segmentation modules to jointly analyze sperm morphology and motility.
Jiajin Li, Wenwen Sun, Jun He, Xinyu Fan, Xuecheng Ge, Fengya Lu, Yadan Wang, Yi Wang, Zhiguo Zhang, Qibing Wu, Jinhua Zhou   +10 more
wiley   +1 more source

Patient Perspectives on Psychiatric Polygenic Risk Scores in Reproductive Decision‐Making and Polygenic Embryo Screening

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Polygenic risk scores (PRS) estimate individuals' genetic risk for developing multifactorial conditions. Recent genome‐wide association studies have enabled development of psychiatric PRS, which hold potential to streamline diagnosis and treatment of psychiatric conditions.
Lauren A. Ginn, Amanda R. Merner, Page M. Trotter, Kaitlynn P. Craig, Abigail C. Martinez, Ana Lucía Battaglino, Dorit Barlevy, Daphne M. Ayton, Takahiro Soda, Eric A. Storch, Gabriel Lázaro‐Muñoz, Stacey Pereira   +11 more
wiley   +1 more source

Facilitating Genetic Testing for Perinatal Demise: Development of a Multidisciplinary Workflow

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Genetic contributors to perinatal demise are common but frequently undiagnosed due to clinical and logistical barriers. We aimed to improve access to genetic for intrauterine fetal demise (IUFD), stillbirth, and early neonatal death by developing a multidisciplinary workflow.
Mackenzie Mosera, Samantha Stover, Elise Boos, Molly Casey, Joseph Fanning, Chelsea Fechter, Matthew Grace, L. Dupree Hatch, Michaela Ibach, Carla Jackson, Jiancong Liang, Caitlin Mann, Emily A. Morris, Jessica Turnbull, Marie Williams, Bryce A. Schuler   +15 more
wiley   +1 more source

Die »Notwendigkeit eines Vaters für das Kind« und der Zugang lesbischer Frauen zur Reproduktionsmedizin (The child’s need for a father and access to assisted reproductive technologies by lesbians) [PDF]

, 2010
This chapter provides an overview of two broad areas relating to lesbians’ use of reproductive services for family building. First, it identifies strategies used in the building of ‘planned’ lesbian families – where a lesbian couple, the genetic mother ...
Blyth, Eric
core  

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source